Dvorak NM - Search Results

1

Fibroblast growth factor 13-mediated regulation of medium spiny neuron excitability and cocaine self-administration.

Dvorak NM, Di Re J, Vasquez TES, Marosi M, Shah P, Contreras YMM, Bernabucci M, Singh AK, Stallone J, Green TA, Laezza F. Dvorak NM, et al. Front Neurosci. 2023 Nov 30;17:1294567. doi: 10.3389/fnins.2023.1294567. eCollection 2023. Front Neurosci. 2023. PMID: 38099204 Free PMC article.

2

Differential Modulation of the Voltage-Gated Na⁺ Channel 1.6 by Peptides Derived From Fibroblast Growth Factor 14.

Singh AK, Dvorak NM, Tapia CM, Mosebarger A, Ali SR, Bullock Z, Chen H, Zhou J, Laezza F. Singh AK, et al. Among authors: dvorak nm. Front Mol Biosci. 2021 Sep 7;8:742903. doi: 10.3389/fmolb.2021.742903. eCollection 2021. Front Mol Biosci. 2021. PMID: 34557523 Free PMC article.

3

Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na⁺ Channel 1.2 Macromolecular Complex.

Dvorak NM, Tapia CM, Baumgartner TJ, Singh J, Laezza F, Singh AK. Dvorak NM, et al. Cells. 2021 Nov 10;10(11):3103. doi: 10.3390/cells10113103. Cells. 2021. PMID: 34831326 Free PMC article.

4

Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na⁺ Channel 1.6 Enables Isoform-Selective Modulation.

Dvorak NM, Tapia CM, Singh AK, Baumgartner TJ, Wang P, Chen H, Wadsworth PA, Zhou J, Laezza F. Dvorak NM, et al. Int J Mol Sci. 2021 Dec 17;22(24):13541. doi: 10.3390/ijms222413541. Int J Mol Sci. 2021. PMID: 34948337 Free PMC article.

5

Inhibition of the Akt/PKB Kinase Increases Na_v1.6-Mediated Currents and Neuronal Excitability in CA1 Hippocampal Pyramidal Neurons.

Marosi M, Nenov MN, Di Re J, Dvorak NM, Alshammari M, Laezza F. Marosi M, et al. Among authors: dvorak nm. Int J Mol Sci. 2022 Feb 1;23(3):1700. doi: 10.3390/ijms23031700. Int J Mol Sci. 2022. PMID: 35163623 Free PMC article.

6

JAK2 regulates Nav1.6 channel function via FGF14^Y158 phosphorylation.

Wadsworth PA, Singh AK, Nguyen N, Dvorak NM, Tapia CM, Russell WK, Stephan C, Laezza F. Wadsworth PA, et al. Among authors: dvorak nm. Biochim Biophys Acta Mol Cell Res. 2020 Oct;1867(10):118786. doi: 10.1016/j.bbamcr.2020.118786. Epub 2020 Jun 26. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32599005 Free PMC article.

7

Development of Allosteric Modulators of Voltage-Gated Na⁺ Channels: A Novel Approach for an Old Target.

Dvorak NM, Wadsworth PA, Wang P, Zhou J, Laezza F. Dvorak NM, et al. Curr Top Med Chem. 2021;21(10):841-848. doi: 10.2174/1568026621666210525105359. Curr Top Med Chem. 2021. PMID: 34036922 Free PMC article. Review.

8

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics.

Dvorak NM, Wadsworth PA, Wang P, Chen H, Zhou J, Laezza F. Dvorak NM, et al. Molecules. 2020 Jul 24;25(15):3365. doi: 10.3390/molecules25153365. Molecules. 2020. PMID: 32722255 Free PMC article.

9

Voltage-Gated Na⁺ Channels in Alzheimer's Disease: Physiological Roles and Therapeutic Potential.

Baumgartner TJ, Haghighijoo Z, Goode NA, Dvorak NM, Arman P, Laezza F. Baumgartner TJ, et al. Among authors: dvorak nm. Life (Basel). 2023 Jul 29;13(8):1655. doi: 10.3390/life13081655. Life (Basel). 2023. PMID: 37629512 Free PMC article. Review.

10

Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6.

Wang P, Wadsworth PA, Dvorak NM, Singh AK, Chen H, Liu Z, Zhou R, Holthauzen LMF, Zhou J, Laezza F. Wang P, et al. Among authors: dvorak nm. J Med Chem. 2020 Oct 22;63(20):11522-11547. doi: 10.1021/acs.jmedchem.0c00531. Epub 2020 Oct 15. J Med Chem. 2020. PMID: 33054193 Free PMC article.

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