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Page 1
Photoredox-catalysed hydroaminoalkylation of on-DNA N-arylamines.
Mahdavi-Amiri Y, Hu MSJ, Frias N, Movahedi M, Csakai A, Marcaurelle LA, Hili R. Mahdavi-Amiri Y, et al. Among authors: csakai a. Org Biomol Chem. 2023 Feb 15;21(7):1463-1467. doi: 10.1039/d2ob01956f. Org Biomol Chem. 2023. PMID: 36655521
Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library.
Rowley AM, Yao G, Andrews L, Bedermann A, Biddulph R, Bingham R, Brady JJ, Buxton R, Cecconie T, Cooper R, Csakai A, Gao EN, Grenier-Davies MC, Lawler M, Lian Y, Macina J, Macphee C, Marcaurelle L, Martin J, McCormick P, Pindoria R, Rauch M, Rocque W, Shen Y, Shewchuk LM, Squire M, Stebbeds W, Tear W, Wang X, Ward P, Xiao S. Rowley AM, et al. Among authors: csakai a. J Med Chem. 2024 Feb 8;67(3):2049-2065. doi: 10.1021/acs.jmedchem.3c01562. Epub 2024 Jan 29. J Med Chem. 2024. PMID: 38284310
Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension.
Zhang SS, Larrabee L, Chang AH, Desai S, Sloan L, Wang X, Wu Y, Parvez N, Amaratunga K, Hartman AC, Whitnall A, Mason J, Barton NP, Chu AY, Davitte JM, Csakai AJ, Tibbetts CV, Tolbert AE, O'Keefe H, Polanco J, Foley J, Kmett C, Kehler J, Kozejova G, Wang F, Mayer AP, Koenig P, Foletti D, Pitts SJ, Schnackenberg CG. Zhang SS, et al. Among authors: csakai aj. Sci Rep. 2024 Jun 8;14(1):13209. doi: 10.1038/s41598-024-62804-7. Sci Rep. 2024. PMID: 38851835 Free PMC article.
NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia.
Rajagopal L, Mahjour S, Huang M, Ryan CA, Elzokaky A, Csakai AJ, Orr MJ, Scheidt K, Meltzer HY. Rajagopal L, et al. Among authors: csakai aj. Behav Brain Res. 2023 Oct 2;454:114614. doi: 10.1016/j.bbr.2023.114614. Epub 2023 Aug 10. Behav Brain Res. 2023. PMID: 37572758
Photochemical C-H arylation of heteroarenes for DNA-encoded library synthesis.
Krumb M, Kammer LM, Badir SO, Cabrera-Afonso MJ, Wu VE, Huang M, Csakai A, Marcaurelle LA, Molander GA. Krumb M, et al. Among authors: csakai a. Chem Sci. 2021 Dec 21;13(4):1023-1029. doi: 10.1039/d1sc05683b. eCollection 2022 Jan 26. Chem Sci. 2021. PMID: 35211268 Free PMC article.
Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists.
Yang Y, Csakai A, Jiang S, Smith C, Tanji H, Huang J, Jones T, Sakaniwa K, Broadwell L, Shi C, Soti S, Ohto U, Fang Y, Shen S, Deng F, Shimizu T, Yin H. Yang Y, et al. Among authors: csakai a. Nat Commun. 2021 Jul 16;12(1):4351. doi: 10.1038/s41467-021-24536-4. Nat Commun. 2021. PMID: 34272380 Free PMC article.
14 results