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A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals a major role of BAX in the response to BH3 mimetics.
Durand R, Descamps G, Bellanger C, Dousset C, Maïga S, Alberge JB, Derrien J, Cruard J, Minvielle S, Lilli NL, Godon C, Le Bris Y, Tessoulin B, Amiot M, Gomez-Bougie P, Touzeau C, Moreau P, Chiron D, Moreau-Aubry A, Pellat-Deceunynck C. Durand R, et al. Among authors: moreau p, moreau aubry a. Blood. 2024 Mar 28;143(13):1242-1258. doi: 10.1182/blood.2023021581. Blood. 2024. PMID: 38096363
Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.
Pouleau B, Estoppey C, Suere P, Nallet E, Laurendon A, Monney T, Pais Ferreira D, Drake A, Carretero-Iglesia L, Macoin J, Berret J, Pihlgren M, Doucey MA, Gudi GS, Menon V, Udupa V, Maiti A, Borthakur G, Srivastava A, Blein S, Mbow ML, Matthes T, Kaya Z, Edwards CM, Edwards JR, Menoret E, Kervoëlen C, Pellat-Deceunynck C, Moreau P, Zhukovsky E, Perro M, Chimen M. Pouleau B, et al. Among authors: moreau p. Blood. 2023 Jul 20;142(3):260-273. doi: 10.1182/blood.2022019451. Blood. 2023. PMID: 37192303 Free PMC article.
Author Correction: Acquired resistance to a GPRC5D-directed T-cell engager in multiple myeloma is mediated by genetic or epigenetic target inactivation.
Derrien J, Gastineau S, Frigout A, Giordano N, Cherkaoui M, Gaborit V, Boinon R, Douillard E, Devic M, Magrangeas F, Moreau P, Minvielle S, Touzeau C, Letouzé E. Derrien J, et al. Among authors: moreau p. Nat Cancer. 2023 Nov;4(11):1610. doi: 10.1038/s43018-023-00646-4. Nat Cancer. 2023. PMID: 37684528 No abstract available.
DCE-MRI to distinguish all monoclonal plasma cell disease stages and correlation with diffusion-weighted MRI/PET-based biomarkers in a hybrid simultaneous whole body-2-[18F]FDG-PET/MRI imaging approach.
Jamet B, Necib H, Carlier T, Frampas E, Bazin J, Desfontis PH, Monnet A, Bodet-Milin C, Moreau P, Touzeau C, Kraeber-Bodere F. Jamet B, et al. Among authors: moreau p. Cancer Imaging. 2024 Jul 11;24(1):93. doi: 10.1186/s40644-024-00740-5. Cancer Imaging. 2024. PMID: 38992707 Free PMC article.
ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells.
Carretero-Iglesia L, Hall OJ, Berret J, Pais D, Estoppey C, Chimen M, Monney T, Loyau J, Dreyfus C, Macoin J, Perez C, Menon V, Gruber I, Laurendon A, Caro LN, Gudi GS, Matsuura T, van der Graaf PH, Blein S, Mbow ML, Croasdale-Wood R, Srivastava A, Dyson MR, Matthes T, Kaya Z, Edwards CM, Edwards JR, Maiga S, Pellat-Deceunynck C, Touzeau C, Moreau P, Konto C, Drake A, Zhukovsky EA, Perro M, Pihlgren M. Carretero-Iglesia L, et al. Among authors: moreau p. Nat Cancer. 2024 Oct;5(10):1494-1514. doi: 10.1038/s43018-024-00821-1. Epub 2024 Sep 11. Nat Cancer. 2024. PMID: 39261676 Free PMC article.
Combined inhibition of CTPS1 and ATR is a metabolic vulnerability in p53-deficient myeloma cells.
Durand R, Bellanger C, Descamps G, Dousset C, Maïga S, Derrien J, Thirouard L, Bouard L, Asnagli H, Beer P, Parker A, Gomez-Bougie P, Devilder MC, Moreau P, Touzeau C, Moreau-Aubry A, Chiron D, Pellat-Deceunynck C. Durand R, et al. Among authors: moreau p, moreau aubry a. Hemasphere. 2024 Oct 8;8(10):e70016. doi: 10.1002/hem3.70016. eCollection 2024 Oct. Hemasphere. 2024. PMID: 39380841 Free PMC article.
1,723 results