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Page 1
Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels.
Hooda Y, Sente A, Judy RM, Smalinskaitė L, Peak-Chew SY, Naydenova K, Malinauskas T, Hardwick SW, Chirgadze DY, Aricescu AR, Hegde RS. Hooda Y, et al. Among authors: aricescu ar. bioRxiv [Preprint]. 2024 Nov 15:2024.10.28.620708. doi: 10.1101/2024.10.28.620708. bioRxiv. 2024. PMID: 39553992 Free PMC article. Preprint.
One-step nanoscale expansion microscopy reveals individual protein shapes.
Shaib AH, Chouaib AA, Chowdhury R, Altendorf J, Mihaylov D, Zhang C, Krah D, Imani V, Spencer RKW, Georgiev SV, Mougios N, Monga M, Reshetniak S, Mimoso T, Chen H, Fatehbasharzad P, Crzan D, Saal KA, Alawieh MM, Alawar N, Eilts J, Kang J, Soleimani A, Müller M, Pape C, Alvarez L, Trenkwalder C, Mollenhauer B, Outeiro TF, Köster S, Preobraschenski J, Becherer U, Moser T, Boyden ES, Aricescu AR, Sauer M, Opazo F, Rizzoli SO. Shaib AH, et al. Among authors: aricescu ar. Nat Biotechnol. 2024 Oct 9:10.1038/s41587-024-02431-9. doi: 10.1038/s41587-024-02431-9. Online ahead of print. Nat Biotechnol. 2024. PMID: 39385007 Free PMC article.
Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes.
Nonaka H, Mino T, Sakamoto S, Oh JH, Watanabe Y, Ishikawa M, Tsushima A, Amaike K, Kiyonaka S, Tamura T, Aricescu AR, Kakegawa W, Miura E, Yuzaki M, Hamachi I. Nonaka H, et al. Among authors: aricescu ar. Chem. 2023 Feb;9(2):523-540. doi: 10.1016/j.chempr.2022.11.005. Chem. 2023. PMID: 38094901 Free PMC article.
GluD1 binds GABA and controls inhibitory plasticity.
Piot L, Heroven C, Bossi S, Zamith J, Malinauskas T, Johnson C, Wennagel D, Stroebel D, Charrier C, Aricescu AR, Mony L, Paoletti P. Piot L, et al. Among authors: aricescu ar. Science. 2023 Dec 22;382(6677):1389-1394. doi: 10.1126/science.adf3406. Epub 2023 Dec 7. Science. 2023. PMID: 38060673
The molecular basis of drug selectivity for α5 subunit-containing GABAA receptors.
Kasaragod VB, Malinauskas T, Wahid AA, Lengyel J, Knoflach F, Hardwick SW, Jones CF, Chen WN, Lucas X, El Omari K, Chirgadze DY, Aricescu AR, Cecere G, Hernandez MC, Miller PS. Kasaragod VB, et al. Among authors: aricescu ar. Nat Struct Mol Biol. 2023 Dec;30(12):1936-1946. doi: 10.1038/s41594-023-01133-1. Epub 2023 Oct 30. Nat Struct Mol Biol. 2023. PMID: 37903907 Free PMC article.
Differential assembly diversifies GABAA receptor structures and signalling.
Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR. Sente A, et al. Among authors: aricescu ar. Nature. 2022 Apr;604(7904):190-194. doi: 10.1038/s41586-022-04517-3. Epub 2022 Mar 30. Nature. 2022. PMID: 35355020 Free PMC article.
Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice.
Salzer R, Clark JJ, Vaysburd M, Chang VT, Albecka A, Kiss L, Sharma P, Gonzalez Llamazares A, Kipar A, Hiscox JA, Owen A, Aricescu AR, Stewart JP, James LC, Löwe J. Salzer R, et al. Among authors: aricescu ar. FEBS Lett. 2021 Sep;595(18):2323-2340. doi: 10.1002/1873-3468.14171. Epub 2021 Aug 22. FEBS Lett. 2021. PMID: 34331769 Free PMC article.
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof MH, Düdükcü Ö, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C. Robinson RA, et al. Among authors: aricescu ar. Cell. 2021 Apr 15;184(8):2103-2120.e31. doi: 10.1016/j.cell.2021.02.045. Epub 2021 Mar 18. Cell. 2021. PMID: 33740419 Free PMC article.
Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Elegheert J, Cvetkovska V, Clayton AJ, Heroven C, Vennekens KM, Smukowski SN, Regan MC, Jia W, Smith AC, Furukawa H, Savas JN, de Wit J, Begbie J, Craig AM, Aricescu AR. Elegheert J, et al. Among authors: aricescu ar. Neuron. 2021 Jan 6;109(1):189-190. doi: 10.1016/j.neuron.2020.12.006. Neuron. 2021. PMID: 33412094 Free PMC article. No abstract available.
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Uchański T, Masiulis S, Fischer B, Kalichuk V, López-Sánchez U, Zarkadas E, Weckener M, Sente A, Ward P, Wohlkönig A, Zögg T, Remaut H, Naismith JH, Nury H, Vranken W, Aricescu AR, Pardon E, Steyaert J. Uchański T, et al. Among authors: aricescu ar. Nat Methods. 2021 Jan;18(1):60-68. doi: 10.1038/s41592-020-01001-6. Epub 2021 Jan 6. Nat Methods. 2021. PMID: 33408403 Free PMC article.
78 results