Tyrrell DJ - Search Results

1

Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice.

Song J, Zhang Y, Frieler RA, Andren A, Wood S, Tyrrell DJ, Sajjakulnukit P, Deng JC, Lyssiotis CA, Mortensen RM, Salmon M, Goldstein DR. Song J, et al. Among authors: tyrrell dj. J Clin Invest. 2023 Dec 12;134(3):e173034. doi: 10.1172/JCI173034. J Clin Invest. 2023. PMID: 38085578 Free PMC article.

2

Pathophysiology of heart failure and frailty: a common inflammatory origin?

Bellumkonda L, Tyrrell D, Hummel SL, Goldstein DR. Bellumkonda L, et al. Aging Cell. 2017 Jun;16(3):444-450. doi: 10.1111/acel.12581. Epub 2017 Mar 7. Aging Cell. 2017. PMID: 28266167 Free PMC article. Review.

3

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis.

Tyrrell DJ, Blin MG, Song J, Wood SC, Zhang M, Beard DA, Goldstein DR. Tyrrell DJ, et al. Circ Res. 2020 Jan 31;126(3):298-314. doi: 10.1161/CIRCRESAHA.119.315644. Epub 2019 Dec 9. Circ Res. 2020. PMID: 31818196 Free PMC article.

4

Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6.

Tyrrell DJ, Goldstein DR. Tyrrell DJ, et al. Nat Rev Cardiol. 2021 Jan;18(1):58-68. doi: 10.1038/s41569-020-0431-7. Epub 2020 Sep 11. Nat Rev Cardiol. 2021. PMID: 32918047 Free PMC article. Review.

5

Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature.

Tyrrell DJ, Blin MG, Song J, Wood SC, Goldstein DR. Tyrrell DJ, et al. J Am Heart Assoc. 2020 Dec;9(23):e017820. doi: 10.1161/JAHA.120.017820. Epub 2020 Nov 23. J Am Heart Assoc. 2020. PMID: 33225820 Free PMC article.

6

Aging Alters the Aortic Proteome in Health and Thoracic Aortic Aneurysm.

Tyrrell DJ, Chen J, Li BY, Wood SC, Rosebury-Smith W, Remmer HA, Jiang L, Zhang M, Salmon M, Ailawadi G, Yang B, Goldstein DR. Tyrrell DJ, et al. Arterioscler Thromb Vasc Biol. 2022 Aug;42(8):1060-1076. doi: 10.1161/ATVBAHA.122.317643. Epub 2022 May 5. Arterioscler Thromb Vasc Biol. 2022. PMID: 35510553 Free PMC article.

7

Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.

Hindy G, Tyrrell DJ, Vasbinder A, Wei C, Presswalla F, Wang H, Blakely P, Ozel AB, Graham S, Holton GH, Dowsett J, Fahed AC, Amadi KM, Erne GK, Tekmulla A, Ismail A, Launius C, Sotoodehnia N, Pankow JS, Thørner LW, Erikstrup C, Pedersen OB, Banasik K, Brunak S, Ullum H, Eugen-Olsen J, Ostrowski SR; DBDS Consortium; Haas ME, Nielsen JB, Lotta LA; Regeneron Genetics Center; Engström G, Melander O, Orho-Melander M, Zhao L, Murthy VL, Pinsky DJ, Willer CJ, Heckbert SR, Reiser J, Goldstein DR, Desch KC, Hayek SS. Hindy G, et al. Among authors: tyrrell dj. J Clin Invest. 2022 Dec 15;132(24):e158788. doi: 10.1172/JCI158788. J Clin Invest. 2022. PMID: 36194491 Free PMC article.

8

Age-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis.

Song J, Farris D, Ariza P, Moorjani S, Varghese M, Blin M, Chen J, Tyrrell D, Zhang M, Singer K, Salmon M, Goldstein DR. Song J, et al. Aging Cell. 2023 Feb;22(2):e13783. doi: 10.1111/acel.13783. Epub 2023 Jan 23. Aging Cell. 2023. PMID: 36683460 Free PMC article.

9

Clonally expanded memory CD8⁺ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice.

Tyrrell DJ, Wragg KM, Chen J, Wang H, Song J, Blin MG, Bolding C, Vardaman D 3rd, Giles K, Tidwell H, Ali MA, Janappareddi A, Wood SC, Goldstein DR. Tyrrell DJ, et al. Nat Aging. 2023 Dec;3(12):1576-1590. doi: 10.1038/s43587-023-00515-w. Epub 2023 Nov 23. Nat Aging. 2023. PMID: 37996758

10

Publisher Correction: Clonally expanded memory CD8⁺ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice.

Tyrrell DJ, Wragg KM, Chen J, Wang H, Song J, Blin MG, Bolding C, Vardaman D 3rd, Giles K, Tidwell H, Ali MA, Janappareddi A, Wood SC, Goldstein DR. Tyrrell DJ, et al. Nat Aging. 2024 Aug;4(8):1166. doi: 10.1038/s43587-024-00653-9. Nat Aging. 2024. PMID: 38789547 No abstract available.

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