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393 results

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Page 1
Development of a Practical Nomogram for Personalized Anemia Management in Patients Treated with Ataxia Telangiectasia and Rad3-related Inhibitor Camonsertib.
Rosen E, Yap TA, Lee EK, Højgaard M, Mettu NB, Lheureux S, Carneiro BA, Plummer R, Fretland AJ, Ulanet D, Xu Y, McDougall R, Koehler M, Fontana E. Rosen E, et al. Among authors: koehler m. Clin Cancer Res. 2024 Feb 16;30(4):687-694. doi: 10.1158/1078-0432.CCR-23-2080. Clin Cancer Res. 2024. PMID: 38078898 Free PMC article.
Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results.
Yap TA, Fontana E, Lee EK, Spigel DR, Højgaard M, Lheureux S, Mettu NB, Carneiro BA, Carter L, Plummer R, Cote GM, Meric-Bernstam F, O'Connell J, Schonhoft JD, Wainszelbaum M, Fretland AJ, Manley P, Xu Y, Ulanet D, Rimkunas V, Zinda M, Koehler M, Silverman IM, Reis-Filho JS, Rosen E. Yap TA, et al. Among authors: koehler m. Nat Med. 2023 Jun;29(6):1400-1411. doi: 10.1038/s41591-023-02399-0. Epub 2023 Jun 5. Nat Med. 2023. PMID: 37277454 Free PMC article. Clinical Trial.
Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma.
Mandelker D, Marra A, Zheng-Lin B, Selenica P, Blanco-Heredia J, Zhu Y, Gazzo A, Wong D, Yelskaya Z, Rai V, Somar J, Ostafi S, Mehta N, Yang C, Li Y, Brown DN, da Silva EM, Pei X, Linkov I, Terraf P, Misyura M, Ceyhan-Birsoy O, Ladanyi M, Berger M, Pareja F, Stadler Z, Offit K, Riaz N, Park W, Chou J, Capanu M, Koehler M, Rosen E, O'Reilly EM, Reis-Filho JS. Mandelker D, et al. Among authors: koehler m. J Clin Oncol. 2023 Nov 20;41(33):5151-5162. doi: 10.1200/JCO.23.00561. Epub 2023 Aug 22. J Clin Oncol. 2023. PMID: 37607324 Free PMC article.
Ataxia telangiectasia and Rad3-related (ATR) inhibitor camonsertib dose optimization in patients with biomarker-selected advanced solid tumors (TRESR study).
Fontana E, Rosen E, Lee EK, Højgaard M, Mettu NB, Lheureux S, Carneiro BA, Cote GM, Carter L, Plummer R, Mahalingam D, Fretland AJ, Schonhoft JD, Silverman IM, Wainszelbaum M, Xu Y, Ulanet D, Koehler M, Yap TA. Fontana E, et al. Among authors: koehler m. J Natl Cancer Inst. 2024 Sep 1;116(9):1439-1449. doi: 10.1093/jnci/djae098. J Natl Cancer Inst. 2024. PMID: 38710487 Free PMC article. Clinical Trial.
Genotype-Directed Synthetic Cytotoxicity of ATR Inhibition with Radiotherapy.
Ng V, Sinha S, Novaj A, Ma J, McDermott N, Pei X, Longhini ALF, Grimsley H, Gardner R, Rosen E, Powell SN, Pareja F, Mandelker D, Khan A, Setton J, Roulston A, Morris S, Koehler M, Lee N, Reis-Filho J, Riaz N. Ng V, et al. Among authors: koehler m. Clin Cancer Res. 2024 Dec 16;30(24):5643-5656. doi: 10.1158/1078-0432.CCR-24-0154. Clin Cancer Res. 2024. PMID: 39109923
ATM Germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications.
El Jabbour T, Misyura M, Cowzer D, Zimmermann M, Rimkunas V, Marra A, Derakhshan F, Selenica P, Parilla M, Setton JS, Ceyhan-Birsoy O, Kemel Y, Catchings A, Ranganathan M, Ku GY, Janjigian YY, Zinda M, Koehler M, Stadler Z, Shia J, Reis-Filho JS, Mandelker D. El Jabbour T, et al. Among authors: koehler m. J Natl Cancer Inst. 2022 May 9;114(5):761-770. doi: 10.1093/jnci/djac024. J Natl Cancer Inst. 2022. PMID: 35078243 Free PMC article.
Synthetic Lethality in Cancer Therapeutics: The Next Generation.
Setton J, Zinda M, Riaz N, Durocher D, Zimmermann M, Koehler M, Reis-Filho JS, Powell SN. Setton J, et al. Among authors: koehler m. Cancer Discov. 2021 Jul;11(7):1626-1635. doi: 10.1158/2159-8290.CD-20-1503. Epub 2021 Apr 1. Cancer Discov. 2021. PMID: 33795234 Free PMC article. Review.
Detection of Biallelic Loss of DNA Repair Genes in Formalin-Fixed, Paraffin-Embedded Tumor Samples Using a Novel Tumor-Only Sequencing Panel.
Glodzik D, Selenica P, Rogge RA, Silverman IM, Mandelker D, Harris S, Zhao J, Zinda M, Veloso A, Malani N, Riaz N, Koehler M, Daber RD, Johnson V, Rimkunas V, Reis-Filho JS. Glodzik D, et al. Among authors: koehler m. J Mol Diagn. 2023 May;25(5):295-310. doi: 10.1016/j.jmoldx.2023.02.004. Epub 2023 Mar 20. J Mol Diagn. 2023. PMID: 36944408 Free PMC article.
Imaging interlayer exciton superfluidity in a 2D semiconductor heterostructure.
Cutshall J, Mahdikhany F, Roche A, Shanks DN, Koehler MR, Mandrus DG, Taniguchi T, Watanabe K, Zhu Q, LeRoy BJ, Schaibley JR. Cutshall J, et al. Among authors: koehler mr. Sci Adv. 2025 Jan 3;11(1):eadr1772. doi: 10.1126/sciadv.adr1772. Epub 2025 Jan 3. Sci Adv. 2025. PMID: 39752490 Free PMC article.
Telemonitoring for Chronic Heart Failure: Narrative Review of the 20-Year Journey From Concept to Standard Care in Germany.
Spethmann S, Hindricks G, Koehler K, Stoerk S, Angermann CE, Böhm M, Assmus B, Winkler S, Möckel M, Mittermaier M, Lelgemann M, Reuter D, Bosch R, Albrecht A, von Haehling S, Helms TM, Sack S, Bekfani T, Gröschel JW, Koehler M, Melzer C, Wintrich J, Zippel-Schultz B, Ertl G, Vogelmeier C, Dagres N, Zernikow J, Koehler F. Spethmann S, et al. Among authors: koehler m. J Med Internet Res. 2024 Dec 4;26:e63391. doi: 10.2196/63391. J Med Internet Res. 2024. PMID: 39631073 Free PMC article. Review.
393 results