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A measles and rubella vaccine microneedle patch in The Gambia: a phase 1/2, double-blind, double-dummy, randomised, active-controlled, age de-escalation trial.
Adigweme I, Yisa M, Ooko M, Akpalu E, Bruce A, Donkor S, Jarju LB, Danso B, Mendy A, Jeffries D, Segonds-Pichon A, Njie A, Crooke S, El-Badry E, Johnstone H, Royals M, Goodson JL, Prausnitz MR, McAllister DV, Rota PA, Henry S, Clarke E. Adigweme I, et al. Among authors: segonds pichon a. Lancet. 2024 May 11;403(10439):1879-1892. doi: 10.1016/S0140-6736(24)00532-4. Epub 2024 Apr 29. Lancet. 2024. PMID: 38697170 Free PMC article. Clinical Trial.
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Hornigold K, Baker MJ, Machin PA, Chetwynd SA, Johnsson AK, Pantarelli C, Islam P, Stammers M, Crossland L, Oxley D, Okkenhaug H, Walker S, Walker R, Segonds-Pichon A, Fukui Y, Malliri A, Welch HCE. Hornigold K, et al. Among authors: segonds pichon a. Front Immunol. 2023 Nov 21;14:1223653. doi: 10.3389/fimmu.2023.1223653. eCollection 2023. Front Immunol. 2023. PMID: 38077328 Free PMC article.
Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes.
Mielczarek O, Rogers CH, Zhan Y, Matheson LS, Stubbington MJT, Schoenfelder S, Bolland DJ, Javierre BM, Wingett SW, Várnai C, Segonds-Pichon A, Conn SJ, Krueger F, Andrews S, Fraser P, Giorgetti L, Corcoran AE. Mielczarek O, et al. Among authors: segonds pichon a. Cell Rep. 2023 Sep 26;42(9):113074. doi: 10.1016/j.celrep.2023.113074. Epub 2023 Sep 6. Cell Rep. 2023. PMID: 37676766 Free PMC article.
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
Chessa TAM, Jung P, Anwar A, Suire S, Anderson KE, Barneda D, Kielkowska A, Sadiq BA, Lai IW, Felisbino S, Turnham DJ, Pearson HB, Phillips WA, Sasaki J, Sasaki T, Oxley D, Spensberger D, Segonds-Pichon A, Wilson M, Walker S, Okkenhaug H, Cosulich S, Hawkins PT, Stephens LR. Chessa TAM, et al. Among authors: segonds pichon a. Mol Cell. 2023 Aug 17;83(16):2991-3009.e13. doi: 10.1016/j.molcel.2023.07.015. Epub 2023 Aug 10. Mol Cell. 2023. PMID: 37567175 Free article.
Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis.
Machin PA, Johnsson AE, Massey EJ, Pantarelli C, Chetwynd SA, Chu JY, Okkenhaug H, Segonds-Pichon A, Walker S, Malliri A, Fukui Y, Welch HCE. Machin PA, et al. Among authors: segonds pichon a. Front Immunol. 2023 Jun 13;14:1180886. doi: 10.3389/fimmu.2023.1180886. eCollection 2023. Front Immunol. 2023. PMID: 37383235 Free PMC article.
Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes.
Suriyalaksh M, Raimondi C, Mains A, Segonds-Pichon A, Mukhtar S, Murdoch S, Aldunate R, Krueger F, Guimerà R, Andrews S, Sales-Pardo M, Casanueva O. Suriyalaksh M, et al. Among authors: segonds pichon a. iScience. 2021 Dec 20;25(1):103663. doi: 10.1016/j.isci.2021.103663. eCollection 2022 Jan 21. iScience. 2021. PMID: 35036864 Free PMC article.
43 results