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The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Hornigold K, Baker MJ, Machin PA, Chetwynd SA, Johnsson AK, Pantarelli C, Islam P, Stammers M, Crossland L, Oxley D, Okkenhaug H, Walker S, Walker R, Segonds-Pichon A, Fukui Y, Malliri A, Welch HCE. Hornigold K, et al. Among authors: okkenhaug h. Front Immunol. 2023 Nov 21;14:1223653. doi: 10.3389/fimmu.2023.1223653. eCollection 2023. Front Immunol. 2023. PMID: 38077328 Free PMC article.
The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy.
Thienpont B, Aronsen JM, Robinson EL, Okkenhaug H, Loche E, Ferrini A, Brien P, Alkass K, Tomasso A, Agrawal A, Bergmann O, Sjaastad I, Reik W, Roderick HL. Thienpont B, et al. Among authors: okkenhaug h. J Clin Invest. 2017 Jan 3;127(1):335-348. doi: 10.1172/JCI88353. Epub 2016 Nov 28. J Clin Invest. 2017. PMID: 27893464 Free PMC article.
Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy.
Drawnel FM, Wachten D, Molkentin JD, Maillet M, Aronsen JM, Swift F, Sjaastad I, Liu N, Catalucci D, Mikoshiba K, Hisatsune C, Okkenhaug H, Andrews SR, Bootman MD, Roderick HL. Drawnel FM, et al. Among authors: okkenhaug h. J Cell Biol. 2012 Nov 26;199(5):783-98. doi: 10.1083/jcb.201111095. Epub 2012 Nov 19. J Cell Biol. 2012. PMID: 23166348 Free PMC article.
Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe.
Sipthorp J, Lebraud H, Gilley R, Kidger AM, Okkenhaug H, Saba-El-Leil M, Meloche S, Caunt CJ, Cook SJ, Heightman TD. Sipthorp J, et al. Among authors: okkenhaug h. Bioconjug Chem. 2017 Jun 21;28(6):1677-1683. doi: 10.1021/acs.bioconjchem.7b00152. Epub 2017 May 12. Bioconjug Chem. 2017. PMID: 28449575 Free article.
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.
Odle RI, Walker SA, Oxley D, Kidger AM, Balmanno K, Gilley R, Okkenhaug H, Florey O, Ktistakis NT, Cook SJ. Odle RI, et al. Among authors: okkenhaug h. Mol Cell. 2020 Jan 16;77(2):228-240.e7. doi: 10.1016/j.molcel.2019.10.016. Epub 2019 Nov 13. Mol Cell. 2020. PMID: 31733992 Free PMC article.
Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans.
Chauve L, Hodge F, Murdoch S, Masoudzadeh F, Mann HJ, Lopez-Clavijo AF, Okkenhaug H, West G, Sousa BC, Segonds-Pichon A, Li C, Wingett SW, Kienberger H, Kleigrewe K, de Bono M, Wakelam MJO, Casanueva O. Chauve L, et al. Among authors: okkenhaug h. PLoS Biol. 2021 Nov 1;19(11):e3001431. doi: 10.1371/journal.pbio.3001431. eCollection 2021 Nov. PLoS Biol. 2021. PMID: 34723964 Free PMC article.
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