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Page 1
Genetic architecture reconciles linkage and association studies of complex traits.
Sidorenko J, Couvy-Duchesne B, Kemper KE, Moen GH, Bhatta L, Åsvold BO, Mägi R; Estonian Biobank Research Team; Ani A, Wang R, Nolte IM; Lifelines Cohort Study; Gordon S, Hayward C, Campbell A, Benjamin DJ, Cesarini D, Evans DM, Goddard ME, Haley CS, Porteous D, Medland SE, Martin NG, Snieder H, Metspalu A, Hveem K, Brumpton B, Visscher PM, Yengo L. Sidorenko J, et al. Among authors: medland se. Nat Genet. 2024 Oct 7. doi: 10.1038/s41588-024-01940-2. Online ahead of print. Nat Genet. 2024. PMID: 39375568
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Vasquez AA, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MP, Boomsma DI, Brodaty H, Brouwer RM, Buitelaar JK, Burkhardt R, Cahn W, Calhoun VD, Carmichael OT, Chakravarty M, Chen Q, Ching CRK, Cichon S, Crespo-Facorro B, Crivello F, Dale AM, Smith GD, de Geus EJ, De Jager PL, de Zubicaray GI, Debette S, DeCarli C, Depondt C, Desrivières S, Djurovic S, Ehrlich S, Erk S, Espeseth T, Fernández G, Filippi I, Fisher SE, Fleischman DA, Fletcher E, Fornage M, Forstner AJ, Francks C, Franke B, Ge T, Goldman AL, Grabe HJ, Green RC, Grimm O, Groenewold NA, Gruber O, Gudnason V, Håberg AK, Haukvik UK, Heinz A, Hibar DP, Hilal S, Himali JJ, Ho BC, Hoehn DF, Hoekstra PJ, Hofer E, Hoffmann W, Holmes AJ, Homuth G, Hosten N, Ikram MK, Ipser JC, Jack CR Jr, Jahanshad N, Jönsson EG, Kahn RS, Kanai R, Klein M, Knol MJ, Launer LJ, Lawrie SM, Hellard SL, Lee PH, Lemaître H, Li S, Liewald DC, Lin H, Longstreth WT Jr, Lopez OL, Luciano M, Maillard P, Marquand AF, Martin NG, Martinot JL, Mather KA, Mattay VS, … See abstract for full author list ➔ García-Marín LM, et al. Among authors: medland se. medRxiv [Preprint]. 2024 Aug 15:2024.08.13.24311922. doi: 10.1101/2024.08.13.24311922. medRxiv. 2024. PMID: 39371125 Free PMC article. Preprint.
Protocol for Cancloz: multicentre randomised, placebo-controlled, double-blind, parallel-group adaptive trial of cannabidiol for clozapine-resistant schizophrenia.
Siskind D, Bull C, Suetani S, Warren N, Suraev A, McGregor I, Kisely S, De Monte V, Trott M, Shine M, Moudgil V, Robinson G, Parker S, Krishnaiah R, Stedman T, Drummond A, Medland S, Iyer R, Baker A. Siskind D, et al. Among authors: medland s. BJPsych Open. 2024 Oct 3;10(5):e156. doi: 10.1192/bjo.2024.748. BJPsych Open. 2024. PMID: 39359160 Free article.
Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts.
Adams MJ, Thorp JG, Jermy BS, Kwong ASF, Kõiv K, Grotzinger AD, Nivard MG, Marshall S, Milaneschi Y, Baune BT, Müller-Myhsok B, Penninx BWJH, Boomsma DI, Levinson DF, Breen G, Pistis G, Grabe HJ, Tiemeier H, Berger K, Rietschel M, Magnusson PK, Uher R, Hamilton SP, Lucae S, Lehto K, Li QS, Byrne EM, Hickie IB, Martin NG, Medland SE, Wray NR, Tucker-Drob EM; Estonian Biobank Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Lewis CM, McIntosh AM, Derks EM. Adams MJ, et al. Among authors: medland se. Psychol Med. 2024 Sep 26:1-10. doi: 10.1017/S0033291724001880. Online ahead of print. Psychol Med. 2024. PMID: 39324397
A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner.
Boltz TA, Chu BB, Liao C, Sealock JM, Ye R, Majara L, Fu JM, Service S, Zhan L, Medland SE, Chapman SB, Rubinacci S, DeFelice M, Grimsby JL, Abebe T, Alemayehu M, Ashaba FK, Atkinson EG, Bigdeli T, Bradway AB, Brand H, Chibnik LB, Fekadu A, Gatzen M, Gelaye B, Gichuru S, Gildea ML, Hill TC, Huang H, Hubbard KM, Injera WE, James R, Joloba M, Kachulis C, Kalmbach PR, Kamulegeya R, Kigen G, Kim S, Koen N, Kwobah EK, Kyebuzibwa J, Lee S, Lennon NJ, Lind PA, Lopera-Maya EA, Makale J, Mangul S, McMahon J, Mowlem P, Musinguzi H, Mwema RM, Nakasujja N, Newman CP, Nkambule LL, O'Neil CR, Olivares AM, Olsen CM, Ongeri L, Parsa SJ, Pretorius A, Ramesar R, Reagan FL, Sabatti C, Schneider JA, Shiferaw W, Stevenson A, Stricker E, Stroud RE 2nd, Tang J, Whiteman D, Yohannes MT, Yu M, Yuan K; NeuroGAP-Psychosis; Akena D, Atwoli L, Kariuki SM, Koenen KC, Newton CRJC, Stein DJ, Teferra S, Zingela Z, Pato CN, Pato MT, Lopez-Jaramillo C, Freimer N, Ophoff RA, Olde Loohuis LM, Talkowski ME, Neale BM, Howrigan DP, Martin AR. Boltz TA, et al. Among authors: medland se. bioRxiv [Preprint]. 2024 Sep 8:2024.09.06.611689. doi: 10.1101/2024.09.06.611689. bioRxiv. 2024. PMID: 39282356 Free PMC article. Preprint.
Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli.
Mosley PE, van der Meer JN, Hamilton LHW, Fripp J, Parker S, Jeganathan J, Breakspear M, Parker R, Holland R, Mitchell BL, Byrne E, Hickie IB, Medland SE, Martin NG, Cocchi L. Mosley PE, et al. Among authors: medland se. Mol Psychiatry. 2024 Aug 27. doi: 10.1038/s41380-024-02699-y. Online ahead of print. Mol Psychiatry. 2024. PMID: 39191867
The Genetic Architecture of the Human Corpus Callosum and its Subregions.
Bhatt RR, Gadewar SP, Shetty A, Ba Gari I, Haddad E, Javid S, Ramesh A, Nourollahimoghadam E, Zhu AH, de Leeuw C, Thompson PM, Medland SE, Jahanshad N. Bhatt RR, et al. Among authors: medland se. bioRxiv [Preprint]. 2024 Jul 26:2024.07.22.603147. doi: 10.1101/2024.07.22.603147. bioRxiv. 2024. PMID: 39091796 Free PMC article. Preprint.
Genome-wide meta-analyses of non-response to antidepressants identify novel loci and potential drugs.
Koch E, Jurgenson T, Einarsson G, Mitchell B, Harder A, Garcia-Marin LM, Krebs K, Lin Y, Xiong Y, Research Team EB, Lu Y, Hagg S, Renteria ME, Medland SE, Wray NR, Martin NG, Huebel C, Breen G, Thorgeirsson T, Stefansson H, Stefansson K, Milani L, Andreassen OA, O'Connell KS. Koch E, et al. Among authors: medland se. medRxiv [Preprint]. 2024 Jul 15:2024.07.13.24310361. doi: 10.1101/2024.07.13.24310361. medRxiv. 2024. PMID: 39072048 Free PMC article. Preprint.
488 results