Gee KW - Search Results

1

Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.

Sangadi DK, Sangadi A, Placeres-Uray F, Titus DJ, Johnstone T, Hogenkamp D, Gee KW, Atkins CM. Sangadi DK, et al. Among authors: gee kw. Exp Neurol. 2024 Feb;372:114647. doi: 10.1016/j.expneurol.2023.114647. Epub 2023 Dec 8. Exp Neurol. 2024. PMID: 38070724

2

Enhancing cognitive recovery in chronic traumatic brain injury through simultaneous allosteric modulation of α7 nicotinic acetylcholine and α5 GABA_A receptors.

Balleste AF, Sangadi A, Titus DJ, Johnstone T, Hogenkamp D, Gee KW, Atkins CM. Balleste AF, et al. Among authors: gee kw. Exp Neurol. 2024 Sep;379:114879. doi: 10.1016/j.expneurol.2024.114879. Epub 2024 Jun 26. Exp Neurol. 2024. PMID: 38942266

3

Allosteric modulators of the δ GABA_A receptor subtype demonstrate a therapeutic effect in morphine-antinociceptive tolerance and withdrawal in mice.

Genaro K, Yoshimura RF, Doan BP, Johnstone TB, Hogenkamp DJ, Gee KW. Genaro K, et al. Among authors: gee kw. Neuropharmacology. 2022 Nov 15;219:109221. doi: 10.1016/j.neuropharm.2022.109221. Epub 2022 Sep 7. Neuropharmacology. 2022. PMID: 36084794 Free PMC article.

4

Realising the therapeutic potential of neuroactive steroid modulators of the GABA_A receptor.

Belelli D, Hogenkamp D, Gee KW, Lambert JJ. Belelli D, et al. Among authors: gee kw. Neurobiol Stress. 2019 Dec 23;12:100207. doi: 10.1016/j.ynstr.2019.100207. eCollection 2020 May. Neurobiol Stress. 2019. PMID: 32435660 Free PMC article.

5

Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury.

Titus DJ, Johnstone T, Johnson NH, London SH, Chapalamadugu M, Hogenkamp D, Gee KW, Atkins CM. Titus DJ, et al. Among authors: gee kw. PLoS One. 2019 Oct 3;14(10):e0223180. doi: 10.1371/journal.pone.0223180. eCollection 2019. PLoS One. 2019. PMID: 31581202 Free PMC article.

6

Enaminone Modulators of Extrasynaptic α₄β₃δ γ-Aminobutyric Acid_A Receptors Reverse Electrographic Status Epilepticus in the Rat After Acute Organophosphorus Poisoning.

Johnstone TBC, McCarren HS, Spampanato J, Dudek FE, McDonough JH, Hogenkamp D, Gee KW. Johnstone TBC, et al. Among authors: gee kw. Front Pharmacol. 2019 May 24;10:560. doi: 10.3389/fphar.2019.00560. eCollection 2019. Front Pharmacol. 2019. PMID: 31178732 Free PMC article.

7

Positive allosteric modulators of nonbenzodiazepine γ-aminobutyric acidA receptor subtypes for the treatment of chronic pain.

Johnstone TBC, Xie JY, Qu C, Wasiak DJ, Hogenkamp DJ, Porreca F, Gee KW. Johnstone TBC, et al. Among authors: gee kw. Pain. 2019 Jan;160(1):198-209. doi: 10.1097/j.pain.0000000000001392. Pain. 2019. PMID: 30204648 Free PMC article.

8

Role of β_2/3-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis.

Reddy DS, Yoshimura RF, Ramanathan G, Carver C, Johnstone TB, Hogenkamp DJ, Gee KW. Reddy DS, et al. Among authors: gee kw. Epilepsy Behav. 2018 May;82:57-63. doi: 10.1016/j.yebeh.2018.02.020. Epub 2018 Mar 26. Epilepsy Behav. 2018. PMID: 29587186

9

Allosteric modulation of nicotinic and GABA_A receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model.

Yoshimura RF, Tran MB, Hogenkamp DJ, Ayala NL, Johnstone T, Dunnigan AJ, Gee TK, Gee KW. Yoshimura RF, et al. Among authors: gee kw. Neuropharmacology. 2017 Nov;126:38-47. doi: 10.1016/j.neuropharm.2017.08.029. Epub 2017 Aug 24. Neuropharmacology. 2017. PMID: 28842344

10

First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288.

Gee KW, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, Tran M, Edmonds SA, Sauer W, Yoshimura R, Johnstone T, Freedman R. Gee KW, et al. J Psychopharmacol. 2017 Apr;31(4):434-441. doi: 10.1177/0269881117691590. Epub 2017 Feb 15. J Psychopharmacol. 2017. PMID: 28196430 Free PMC article. Clinical Trial.

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