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Pharmacokinetic and pharmacodynamic evaluation of the atypical tetracyclines chelocardin and amidochelocardin in murine infection models.
Rox K, Jansen R, Lukežič T, Greweling-Pils M, Herrmann J, Miethke M, Hüttel S, Hennessen F, Abou Fayad A, Holzhausen C, Lundberg CV, Teague J, Sudarman E, Bülter L, Hesterkamp T, Stadler M, Brönstrup M, Müller R. Rox K, et al. Microbiol Spectr. 2024 Jan 11;12(1):e0128923. doi: 10.1128/spectrum.01289-23. Epub 2023 Dec 4. Microbiol Spectr. 2024. PMID: 38047701 Free PMC article.
Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Treatment of Dengue Infections Applied to the Broad Spectrum Antiviral Soraphen A.
Rox K, Heyner M, Krull J, Harmrolfs K, Rinne V, Hokkanen J, Perez Vilaro G, Díez J, Müller R, Kröger A, Sugiyama Y, Brönstrup M. Rox K, et al. ACS Pharmacol Transl Sci. 2021 Aug 30;4(5):1499-1513. doi: 10.1021/acsptsci.1c00078. eCollection 2021 Oct 8. ACS Pharmacol Transl Sci. 2021. PMID: 34661071 Free PMC article.
Sorangicin A Is Active against Chlamydia in Cell Culture, Explanted Fallopian Tubes, and Topical In Vivo Treatment.
Graspeuntner S, Koethke K, Scholz C, Semmler L, Lupatsii M, Kirchhoff L, Herrmann J, Rox K, Wittstein K, Käding N, Hanker LC, Stadler M, Brönstrup M, Müller R, Shima K, Rupp J. Graspeuntner S, et al. Among authors: rox k. Antibiotics (Basel). 2023 Apr 22;12(5):795. doi: 10.3390/antibiotics12050795. Antibiotics (Basel). 2023. PMID: 37237698 Free PMC article.
Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy.
Testolin G, Cirnski K, Rox K, Prochnow H, Fetz V, Grandclaudon C, Mollner T, Baiyoumy A, Ritter A, Leitner C, Krull J, van den Heuvel J, Vassort A, Sordello S, Hamed MM, Elgaher WAM, Herrmann J, Hartmann RW, Müller R, Brönstrup M. Testolin G, et al. Among authors: rox k. Chem Sci. 2019 Dec 10;11(5):1316-1334. doi: 10.1039/c9sc04769g. Chem Sci. 2019. PMID: 34123255 Free PMC article.
Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry.
Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Le Goffic R, Galloux M, Prochnow H, Rox K, Hüttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, Eléouët JF, Duprex WP, Thiel V, Hansen G, Brönstrup M, Haid S, Pietschmann T. Blockus S, et al. Among authors: rox k. Antiviral Res. 2020 May;177:104774. doi: 10.1016/j.antiviral.2020.104774. Epub 2020 Mar 18. Antiviral Res. 2020. PMID: 32197980 Free article.
44 results