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214 results

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Inhibition of T-cell activity in alopecia areata: recent developments and new directions.
Passeron T, King B, Seneschal J, Steinhoff M, Jabbari A, Ohyama M, Tobin DJ, Randhawa S, Winkler A, Telliez JB, Martin D, Lejeune A. Passeron T, et al. Among authors: lejeune a. Front Immunol. 2023 Nov 6;14:1243556. doi: 10.3389/fimmu.2023.1243556. eCollection 2023. Front Immunol. 2023. PMID: 38022501 Free PMC article. Review.
Target Occupancy and Functional Inhibition of JAK3 and TEC Family Kinases by Ritlecitinib in Healthy Adults: An Open-Label, Phase 1 Study.
Martin DA, Telliez JB, Pleasic-Williams S, Zhang Y, Tierney B, Blatnik M, Gale JD, Banfield C, Zhou Y, Lejeune A, Zwillich SH, Stevens E, Tiwari N, Kieras E, Karanam A. Martin DA, et al. Among authors: lejeune a. J Clin Pharmacol. 2024 Jan;64(1):67-79. doi: 10.1002/jcph.2347. Epub 2023 Sep 29. J Clin Pharmacol. 2024. PMID: 37691236 Clinical Trial.
Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program.
King B, Soung J, Tziotzios C, Rudnicka L, Joly P, Gooderham M, Sinclair R, Mesinkovska NA, Paul C, Gong Y, Anway SD, Tran H, Wolk R, Zwillich SH, Lejeune A. King B, et al. Among authors: lejeune a. Am J Clin Dermatol. 2024 Mar;25(2):299-314. doi: 10.1007/s40257-024-00846-3. Epub 2024 Jan 23. Am J Clin Dermatol. 2024. PMID: 38263353 Free PMC article. Clinical Trial.
Correction to: Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program.
King B, Soung J, Tziotzios C, Rudnicka L, Joly P, Gooderham M, Sinclair R, Mesinkovska NA, Paul C, Gong Y, Anway SD, Tran H, Wolk R, Zwillich SH, Lejeune A. King B, et al. Among authors: lejeune a. Am J Clin Dermatol. 2024 Jul;25(4):689. doi: 10.1007/s40257-024-00864-1. Am J Clin Dermatol. 2024. PMID: 38789821 Free PMC article. No abstract available.
Efficacy and safety of the oral Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor ritlecitinib over 24 months: integrated analysis of the ALLEGRO phase IIb/III and long-term phase III clinical studies in alopecia areata.
Piliang M, Soung J, King B, Shapiro J, Rudnicka L, Farrant P, Magnolo N, Piraccini BM, Luo X, Wolk R, Woodworth D, Schaefer G, Lejeune A. Piliang M, et al. Among authors: lejeune a. Br J Dermatol. 2025 Jan 24;192(2):215-227. doi: 10.1093/bjd/ljae365. Br J Dermatol. 2025. PMID: 39432738 Clinical Trial.
Long-term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the ALLEGRO-LT phase 3, open-label study.
Tziotzios C, Sinclair R, Lesiak A, Mehlis S, Kinoshita-Ise M, Tsianakas A, Luo X, Law EH, Ishowo-Adejumo R, Wolk R, Sadrarhami M, Lejeune A. Tziotzios C, et al. Among authors: lejeune a. J Eur Acad Dermatol Venereol. 2025 Jan 23. doi: 10.1111/jdv.20526. Online ahead of print. J Eur Acad Dermatol Venereol. 2025. PMID: 39846397
214 results