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Skeletal muscle-specific inducible AMPKα1/α2 knockout mice develop muscle weakness, glycogen depletion, and fibrosis that persists during disuse atrophy.
Petrocelli JJ, Liu J, Yee EM, Ferrara PJ, Bourrant PE, de Hart NMMP, Tatum SM, Holland WJ, Funai K, Drummond MJ. Petrocelli JJ, et al. Among authors: drummond mj. Am J Physiol Endocrinol Metab. 2024 Jan 1;326(1):E50-E60. doi: 10.1152/ajpendo.00261.2023. Epub 2023 Nov 29. Am J Physiol Endocrinol Metab. 2024. PMID: 38019084 Free PMC article.
MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.
Kwon OS, Tanner RE, Barrows KM, Runtsch M, Symons JD, Jalili T, Bikman BT, McClain DA, O'Connell RM, Drummond MJ. Kwon OS, et al. Among authors: drummond mj. Am J Physiol Endocrinol Metab. 2015 Jul 1;309(1):E11-21. doi: 10.1152/ajpendo.00124.2015. Epub 2015 May 12. Am J Physiol Endocrinol Metab. 2015. PMID: 25968578 Free PMC article. Clinical Trial.
Aging impairs mouse skeletal muscle macrophage polarization and muscle-specific abundance during recovery from disuse.
Reidy PT, McKenzie AI, Mahmassani ZS, Petrocelli JJ, Nelson DB, Lindsay CC, Gardner JE, Morrow VR, Keefe AC, Huffaker TB, Stoddard GJ, Kardon G, O'Connell RM, Drummond MJ. Reidy PT, et al. Among authors: drummond mj. Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E85-E98. doi: 10.1152/ajpendo.00422.2018. Epub 2019 Apr 9. Am J Physiol Endocrinol Metab. 2019. PMID: 30964703 Free PMC article.
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity.
Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K. Heden TD, et al. Among authors: drummond mj. Sci Adv. 2019 Sep 11;5(9):eaax8352. doi: 10.1126/sciadv.aax8352. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31535029 Free PMC article.
Pharmacological inhibition of TLR4 ameliorates muscle and liver ceramide content after disuse in previously physically active mice.
McKenzie AI, Reidy PT, Nelson DS, Mulvey JL, Yonemura NM, Petrocelli JJ, Mahmassani ZS, Tippetts TS, Summers SA, Funai K, Drummond MJ. McKenzie AI, et al. Among authors: drummond mj. Am J Physiol Regul Integr Comp Physiol. 2020 Mar 1;318(3):R503-R511. doi: 10.1152/ajpregu.00330.2019. Epub 2020 Jan 29. Am J Physiol Regul Integr Comp Physiol. 2020. PMID: 31994900 Free PMC article.
Neuromuscular electrical stimulation and protein during bed rest increases CD11b+ skeletal muscle macrophages but does not correspond to muscle size or insulin sensitivity.
Reidy PT, Edvalson LT, McKenzie AI, Petrocelli JJ, Mahmassani ZS, Drummond MJ. Reidy PT, et al. Among authors: drummond mj. Appl Physiol Nutr Metab. 2020 Nov;45(11):1261-1269. doi: 10.1139/apnm-2020-0064. Epub 2020 May 29. Appl Physiol Nutr Metab. 2020. PMID: 32470312 Free PMC article. Clinical Trial.
134 results