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Page 1
An evolutionary perspective on complex neuropsychiatric disease.
McClellan JM, Zoghbi AW, Buxbaum JD, Cappi C, Crowley JJ, Flint J, Grice DE, Gulsuner S, Iyegbe C, Jain S, Kuo PH, Lattig MC, Passos-Bueno MR, Purushottam M, Stein DJ, Sunshine AB, Susser ES, Walsh CA, Wootton O, King MC. McClellan JM, et al. Among authors: iyegbe c. Neuron. 2024 Jan 3;112(1):7-24. doi: 10.1016/j.neuron.2023.10.037. Epub 2023 Nov 27. Neuron. 2024. PMID: 38016473 Free PMC article. Review.
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, … See abstract for full author list ➔ Trubetskoy V, et al. Among authors: iyegbe c. Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. Nature. 2022. PMID: 35396580 Free PMC article.
Methylomic signature of current cannabis use in two first-episode psychosis cohorts.
Dempster EL, Wong CCY, Burrage J, Hannon E, Quattrone D, Trotta G, Rodriguez V, Alameda L, Spinazzola E, Tripoli G, Austin-Zimmerman I, Li Z, Gayer-Anderson C, Freeman TP, Johnson EC, Jongsma HE, Stilo S, La Cascia C, Ferraro L, La Barbera D, Lasalvia A, Tosato S, Tarricone I, D'Andrea G, Galatolo M, Tortelli A, Pompili M, Selten JP, de Haan L, Menezes PR, Del Ben CM, Santos JL, Arrojo M, Bobes J, Sanjuán J, Bernardo M, Arango C, Jones PB, Breen G, Mondelli V, Dazzan P, Iyegbe C, Vassos E, Morgan C, Mukherjee D, van Os J, Rutten B, O'Donovan MC, Sham P, Mill J, Murray R, Di Forti M. Dempster EL, et al. Among authors: iyegbe c. Mol Psychiatry. 2024 Oct 16. doi: 10.1038/s41380-024-02689-0. Online ahead of print. Mol Psychiatry. 2024. PMID: 39406996
Biological Insights from Schizophrenia-associated Loci in Ancestral Populations.
Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Rajeevan N, Sayward F, Cheung KH; Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS); Consortium on the Genomics of Schizophrenia (COGS); Genomic Psychiatry Cohort (GPC) Investigators; DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley P, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN; PsychAD Consortium; Cooperative Studies Program (CSP) #572; Million Veteran Program (MVP); Huang GD, Muralidhar S, Michael Gaziano J, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. Bigdeli TB, et al. Among authors: iyegbe co. medRxiv [Preprint]. 2024 Aug 28:2024.08.27.24312631. doi: 10.1101/2024.08.27.24312631. medRxiv. 2024. PMID: 39252912 Free PMC article. Preprint.
Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population.
Strom NI, Burton CL, Iyegbe C, Silzer T, Antonyan L, Pool R, Lemire M, Crowley JJ, Hottenga JJ, Ivanov VZ, Larsson H, Lichtenstein P, Magnusson P, Rück C, Schachar R, Wu HM, Cath D, Crosbie J, Mataix-Cols D, Boomsma DI, Mattheisen M, Meier SM, Smit DJA, Arnold PD. Strom NI, et al. Among authors: iyegbe c. Mol Psychiatry. 2024 Sep;29(9):2714-2723. doi: 10.1038/s41380-024-02489-6. Epub 2024 Mar 28. Mol Psychiatry. 2024. PMID: 38548983 Free PMC article.
Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis.
Wang B, Irizar H, Thygesen JH, Zartaloudi E, Austin-Zimmerman I, Bhat A, Harju-Seppänen J, Pain O, Bass N, Gkofa V, Alizadeh BZ, van Amelsvoort T, Arranz MJ, Bender S, Cahn W, Stella Calafato M, Crespo-Facorro B, Di Forti M; Genetic Risk and Outcome of Psychosis (GROUP) Study; Giegling I, de Haan L, Hall J, Hall MH, van Haren N, Iyegbe C, Kahn RS, Kravariti E, Lawrie SM, Lin K, Luykx JJ, Mata I, McDonald C, McIntosh AM, Murray RM; Psychosis Endophenotypes International Consortium (PEIC); Picchioni M, Powell J, Prata DP, Rujescu D, Rutten BPF, Shaikh M, Simons CJP, Toulopoulou T, Weisbrod M, van Winkel R, Kuchenbaecker K, McQuillin A, Bramon E. Wang B, et al. Among authors: iyegbe c. Schizophr Bull. 2023 Nov 29;49(6):1625-1636. doi: 10.1093/schbul/sbad088. Schizophr Bull. 2023. PMID: 37582581 Free PMC article.
Serum immune markers and transition to psychosis in individuals at clinical high risk.
Mondelli V, Blackman G, Kempton MJ, Pollak TA, Iyegbe C, Valmaggia LR, Amminger P, Barrantes-Vidal N, Bressan R, van der Gaag M, de Haan L, Krebs MO, Nordentoft M, Ruhrmann S, Riecher-Rössler A, Rutten BPF, Sachs G, Koutsouleris N; EU GEI High Risk Study; McGuire P. Mondelli V, et al. Among authors: iyegbe c. Brain Behav Immun. 2023 May;110:290-296. doi: 10.1016/j.bbi.2023.03.014. Epub 2023 Mar 20. Brain Behav Immun. 2023. PMID: 36940754 Free article.
Correction: Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.
Strom NI, Smit DJA, Silzer T, Iyegbe C, Burton CL, Pool R, Lemire M, Crowley JJ, Hottenga JJ, Ivanov VZ, Larsson H, Lichtenstein P, Magnusson P, Rück C, Schachar RJ, Wu HM, Meier SM, Crosbie J, Arnold PD, Mattheisen M, Boomsma DI, Mataix-Cols D, Cath D. Strom NI, et al. Among authors: iyegbe c. Transl Psychiatry. 2022 Dec 22;12(1):521. doi: 10.1038/s41398-022-02288-z. Transl Psychiatry. 2022. PMID: 36550104 Free PMC article. No abstract available.
Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.
Strom NI, Smit DJA, Silzer T, Iyegbe C, Burton CL, Pool R, Lemire M, Crowley JJ, Hottenga JJ, Ivanov VZ, Larsson H, Lichtenstein P, Magnusson P, Rück C, Schachar RJ, Wu HM, Meier SM, Crosbie J, Arnold PD, Mattheisen M, Boomsma DI, Mataix-Cols D, Cath D. Strom NI, et al. Among authors: iyegbe c. Transl Psychiatry. 2022 Nov 15;12(1):479. doi: 10.1038/s41398-022-02248-7. Transl Psychiatry. 2022. PMID: 36379924 Free PMC article.
Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells.
Bhat A, Irizar H, Couch ACM, Raval P, Duarte RRR, Dutan Polit L, Hanger B, Powell T, Deans PJM, Shum C, Nagy R, McAlonan G, Iyegbe CO, Price J, Bramon E, Bhattacharyya S, Vernon AC, Srivastava DP. Bhat A, et al. Among authors: iyegbe co. Brain Behav Immun. 2022 Oct;105:82-97. doi: 10.1016/j.bbi.2022.06.010. Epub 2022 Jun 16. Brain Behav Immun. 2022. PMID: 35716830 Free PMC article.
58 results