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Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice.
Lei PJ, Ruscic KJ, Roh K, Rajotte JJ, O'Melia MJ, Bouta EM, Marquez M, Pereira ER, Kumar AS, Razavi MS, Zhou H, Menzel L, Huang L, Kumra H, Duquette M, Huang P, Baish JW, Munn LL, Kurpios NA, Ubellacker JM, Padera TP. Lei PJ, et al. Among authors: kumra h. Dev Cell. 2024 Dec 19:S1534-5807(24)00732-9. doi: 10.1016/j.devcel.2024.12.010. Online ahead of print. Dev Cell. 2024. PMID: 39731913
Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer.
Mahat DB, Kumra H, Castro SA, Metcalf E, Nguyen K, Morisue R, Ho WW, Chen I, Sullivan B, Yim LK, Singh A, Fu J, Waterton SK, Cheng YC, Roberge S, Moiso E, Chauhan VP, Silva HM, Spranger S, Jain RK, Sharp PA. Mahat DB, et al. Among authors: kumra h. bioRxiv [Preprint]. 2024 Aug 30:2024.08.28.609802. doi: 10.1101/2024.08.28.609802. bioRxiv. 2024. PMID: 39257788 Free PMC article. Preprint.
Lymphatic muscle cells are unique cells that undergo aging induced changes.
Lei PJ, Ruscic KJ, Roh K, Rajotte JJ, O'Melia MJ, Bouta EM, Marquez M, Pereira ER, Kumar AS, Arroyo-Ataz G, Razavi MS, Zhou H, Menzel L, Kumra H, Duquette M, Huang P, Baish JW, Munn LL, Ubellacker JM, Jones D, Padera TP. Lei PJ, et al. Among authors: kumra h. bioRxiv [Preprint]. 2023 Nov 19:2023.11.18.567621. doi: 10.1101/2023.11.18.567621. bioRxiv. 2023. Update in: Dev Cell. 2024 Dec 19:S1534-5807(24)00732-9. doi: 10.1016/j.devcel.2024.12.010 PMID: 38014141 Free PMC article. Updated. Preprint.
Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer.
Boucher Y, Posada JM, Subudhi S, Kumar AS, Rosario SR, Gu L, Kumra H, Mino-Kenudson M, Talele NP, Duda DG, Fukumura D, Wo JY, Clark JW, Ryan DP, Fernandez-Del Castillo C, Hong TS, Pittet MJ, Jain RK. Boucher Y, et al. Among authors: kumra h. Clin Cancer Res. 2023 Apr 14;29(8):1605-1619. doi: 10.1158/1078-0432.CCR-22-1630. Clin Cancer Res. 2023. PMID: 36749873 Free PMC article. Clinical Trial.
19 results