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Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades.
Dadonaite B, Brown J, McMahon TE, Farrell AG, Asarnow D, Stewart C, Logue J, Murrell B, Chu HY, Veesler D, Bloom JD. Dadonaite B, et al. Among authors: stewart c. bioRxiv [Preprint]. 2023 Nov 14:2023.11.13.566961. doi: 10.1101/2023.11.13.566961. bioRxiv. 2023. Update in: Nature. 2024 Jul;631(8021):617-626. doi: 10.1038/s41586-024-07636-1. PMID: 38014024 Free PMC article. Updated. Preprint.
Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses.
Walls AC, Sprouse KR, Joshi A, Bowen JE, Franko N, Navarro MJ, Stewart C, McCallum M, Goecker EA, Degli-Angeli EJ, Logue J, Greninger A, Chu H, Veesler D. Walls AC, et al. Among authors: stewart c. bioRxiv [Preprint]. 2021 Dec 13:2021.12.08.471707. doi: 10.1101/2021.12.08.471707. bioRxiv. 2021. Update in: Cell. 2022 Mar 3;185(5):872-880.e3. doi: 10.1016/j.cell.2022.01.011. PMID: 34931192 Free PMC article. Updated. Preprint.
SARS-CoV-2 spike conformation determines plasma neutralizing activity.
Bowen JE, Walls AC, Joshi A, Sprouse KR, Stewart C, Tortorici MA, Franko NM, Logue JK, Mazzitelli IG, Tiles SW, Ahmed K, Shariq A, Snell G, Iqbal NT, Geffner J, Bandera A, Gori A, Grifantini R, Chu HY, Van Voorhis WC, Corti D, Veesler D. Bowen JE, et al. Among authors: stewart c. bioRxiv [Preprint]. 2021 Dec 21:2021.12.19.473391. doi: 10.1101/2021.12.19.473391. bioRxiv. 2021. Update in: Sci Immunol. 2022 Dec 23;7(78):eadf1421. doi: 10.1126/sciimmunol.adf1421. PMID: 34981060 Free PMC article. Updated. Preprint.
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Park YJ, Pinto D, Walls AC, Liu Z, Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko N, Logue J, Dang HV, Hauser K, Iulio JD, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu H, Pizzuto MS, Corti D, Veesler D. Park YJ, et al. Among authors: stewart c. bioRxiv [Preprint]. 2022 Aug 22:2022.05.08.491108. doi: 10.1101/2022.05.08.491108. bioRxiv. 2022. Update in: Science. 2022 Nov 11;378(6620):619-627. doi: 10.1126/science.adc9127. PMID: 35677069 Free PMC article. Updated. Preprint.
Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants.
Addetia A, Piccoli L, Case JB, Park YJ, Beltramello M, Guarino B, Dang H, Pinto D, Scheaffer S, Sprouse K, Bassi J, Silacci-Fregni C, Muoio F, Dini M, Vincenzetti L, Acosta R, Johnson D, Subramanian S, Saliba C, Giurdanella M, Lombardo G, Leoni G, Culap K, McAlister C, Rajesh A, Dellota E, Zhou J, Farhat N, Bohan D, Noack J, Lempp FA, Cameroni E, Whitener B, Giannini O, Ceschi A, Ferrari P, Franzetti-Pellanda A, Biggiogero M, Garzoni C, Zappi S, Bernasconi L, Kim MJ, Schnell G, Czudnochowski N, Franko N, Logue JK, Yoshiyama C, Stewart C, Chu H, Schmid MA, Purcell LA, Snell G, Lanzavecchia A, Diamond M, Corti D, Veesler D. Addetia A, et al. Among authors: stewart c. bioRxiv [Preprint]. 2023 Feb 27:2023.01.17.523798. doi: 10.1101/2023.01.17.523798. bioRxiv. 2023. PMID: 36711984 Free PMC article. Preprint.
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Lee J, Zepeda SK, Park YJ, Taylor AL, Quispe J, Stewart C, Leaf EM, Treichel C, Corti D, King NP, Starr TN, Veesler D. Lee J, et al. Among authors: stewart c. bioRxiv [Preprint]. 2023 Sep 13:2023.09.12.557371. doi: 10.1101/2023.09.12.557371. bioRxiv. 2023. Update in: Cell Host Microbe. 2023 Dec 13;31(12):1961-1973.e11. doi: 10.1016/j.chom.2023.10.018. PMID: 37745523 Free PMC article. Updated. Preprint.
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Lee J, Stewart C, Schaefer A, Leaf EM, Park YJ, Asarnow D, Powers JM, Treichel C, Corti D, Baric R, King NP, Veesler D. Lee J, et al. Among authors: stewart c. bioRxiv [Preprint]. 2023 Dec 20:2023.12.12.571160. doi: 10.1101/2023.12.12.571160. bioRxiv. 2023. Update in: Nat Commun. 2024 Jun 28;15(1):5496. doi: 10.1038/s41467-024-49656-5. PMID: 38168207 Free PMC article. Updated. Preprint.
Human coronavirus HKU1 recognition of the TMPRSS2 host receptor.
McCallum M, Park YJ, Stewart C, Sprouse KR, Brown J, Tortorici MA, Gibson C, Wong E, Ieven M, Telenti A, Veesler D. McCallum M, et al. Among authors: stewart c. bioRxiv [Preprint]. 2024 Jan 9:2024.01.09.574565. doi: 10.1101/2024.01.09.574565. bioRxiv. 2024. Update in: Cell. 2024 Aug 8;187(16):4231-4245.e13. doi: 10.1016/j.cell.2024.06.006. PMID: 38260518 Free PMC article. Updated. Preprint.
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Chao CW, Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG, Ahlrichs M, Dobbins C, Hand A, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schäfer A, Veesler D, King NP. Chao CW, et al. Among authors: stewart c. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584735. doi: 10.1101/2024.03.13.584735. bioRxiv. 2024. PMID: 38558973 Free PMC article. Preprint.
Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans.
Addetia A, Stewart C, Seo AJ, Sprouse KR, Asiri AY, Al-Mozaini M, Memish ZA, Alshukairi A, Veesler D. Addetia A, et al. Among authors: stewart c. bioRxiv [Preprint]. 2024 Apr 2:2024.03.31.586409. doi: 10.1101/2024.03.31.586409. bioRxiv. 2024. Update in: Cell Rep. 2024 Aug 27;43(8):114530. doi: 10.1016/j.celrep.2024.114530. PMID: 38617298 Free PMC article. Updated. Preprint.
4,650 results