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Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophages.
Caceres L, Abogunloko T, Malchow S, Ehret F, Merz J, Li X, Sol Mitre L, Magnani N, Tasat D, Mwinyella T, Spiga L, Suchanek D, Fischer L, Gorka O, Colin Gissler M, Hilgendorf I, Stachon P, Rog-Zielinska E, Groß O, Westermann D, Evelson P, Wolf D, Marchini T. Caceres L, et al. Among authors: merz j. Environ Pollut. 2024 Jan 15;341:122997. doi: 10.1016/j.envpol.2023.122997. Epub 2023 Nov 22. Environ Pollut. 2024. PMID: 38000727 Free PMC article.
P2X7 Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice.
Stachon P, Heidenreich A, Merz J, Hilgendorf I, Wolf D, Willecke F, von Garlen S, Albrecht P, Härdtner C, Ehrat N, Hoppe N, Reinöhl J, von Zur Mühlen C, Bode C, Idzko M, Zirlik A. Stachon P, et al. Among authors: merz j. Circulation. 2017 Jun 20;135(25):2524-2533. doi: 10.1161/CIRCULATIONAHA.117.027400. Epub 2017 Apr 4. Circulation. 2017. PMID: 28377486
P2X4 deficiency reduces atherosclerosis and plaque inflammation in mice.
Peikert A, König S, Suchanek D, Rofa K, Schäfer I, Dimanski D, Karnbrock L, Bulatova K, Engelmann J, Hoppe N, Wadle C, Heidt T, Albrecht P, von Garlen S, Härdtner C, Hilgendorf I, Wolf D, von Zur Mühlen C, Bode C, Zirlik A, Duerschmied D, Merz J, Stachon P. Peikert A, et al. Among authors: merz j. Sci Rep. 2022 Feb 18;12(1):2801. doi: 10.1038/s41598-022-06706-6. Sci Rep. 2022. PMID: 35181718 Free PMC article.
Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile.
Merz J, Nettesheim A, von Garlen S, Albrecht P, Saller BS, Engelmann J, Hertle L, Schäfer I, Dimanski D, König S, Karnbrock L, Bulatova K, Peikert A, Hoppe N, Hilgendorf I, von Zur Mühlen C, Wolf D, Groß O, Bode C, Zirlik A, Stachon P. Merz J, et al. Purinergic Signal. 2021 Sep;17(3):481-492. doi: 10.1007/s11302-021-09798-3. Epub 2021 Jul 20. Purinergic Signal. 2021. PMID: 34282551 Free PMC article.
Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe-/- mice.
Leipner J, Dederichs TS, von Ehr A, Rauterberg S, Ehlert C, Merz J, Dufner B, Hoppe N, Krebs K, Heidt T, von Zur Muehlen C, Stachon P, Ley K, Wolf D, Zirlik A, Bode C, Hilgendorf I, Härdtner C. Leipner J, et al. Among authors: merz j. Mol Metab. 2021 Nov;53:101250. doi: 10.1016/j.molmet.2021.101250. Epub 2021 May 12. Mol Metab. 2021. PMID: 33991749 Free PMC article.
Elevated platelet-leukocyte complexes are associated with, but dispensable for myocardial ischemia-reperfusion injury.
Starz C, Härdtner C, Mauler M, Dufner B, Hoppe N, Krebs K, Ehlert CA, Merz J, Heidt T, Stachon P, Wolf D, Bode C, von Zur Muehlen C, Rottbauer W, Gawaz M, Duerschmied D, Leuschner F, Borst O, Westermann D, Hilgendorf I. Starz C, et al. Among authors: merz j. Basic Res Cardiol. 2022 Nov 16;117(1):61. doi: 10.1007/s00395-022-00970-3. Basic Res Cardiol. 2022. PMID: 36383299 Free PMC article.
Residual inflammatory risk in coronary heart disease: incidence of elevated high-sensitive CRP in a real-world cohort.
Peikert A, Kaier K, Merz J, Manhart L, Schäfer I, Hilgendorf I, Hehn P, Wolf D, Willecke F, Sheng X, Clemens A, Zehender M, von Zur Mühlen C, Bode C, Zirlik A, Stachon P. Peikert A, et al. Among authors: merz j. Clin Res Cardiol. 2020 Mar;109(3):315-323. doi: 10.1007/s00392-019-01511-0. Epub 2019 Jul 19. Clin Res Cardiol. 2020. PMID: 31325043 Free PMC article.
282 results