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Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophages.
Caceres L, Abogunloko T, Malchow S, Ehret F, Merz J, Li X, Sol Mitre L, Magnani N, Tasat D, Mwinyella T, Spiga L, Suchanek D, Fischer L, Gorka O, Colin Gissler M, Hilgendorf I, Stachon P, Rog-Zielinska E, Groß O, Westermann D, Evelson P, Wolf D, Marchini T. Caceres L, et al. Among authors: fischer l. Environ Pollut. 2024 Jan 15;341:122997. doi: 10.1016/j.envpol.2023.122997. Epub 2023 Nov 22. Environ Pollut. 2024. PMID: 38000727 Free PMC article.
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis.
Neuwirt E, Magnani G, Ćiković T, Wöhrle S, Fischer L, Kostina A, Flemming S, Fischenich NJ, Saller BS, Gorka O, Renner S, Agarinis C, Parker CN, Boettcher A, Farady CJ, Kesselring R, Berlin C, Backofen R, Rodriguez-Franco M, Kreutz C, Prinz M, Tholen M, Reinheckel T, Ott T, Groß CJ, Jost PJ, Groß O. Neuwirt E, et al. Among authors: fischer l. Sci Signal. 2023 Jan 17;16(768):eabh1083. doi: 10.1126/scisignal.abh1083. Epub 2023 Jan 17. Sci Signal. 2023. PMID: 36649377
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation.
Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. Saller BS, et al. Among authors: fischer l. Immunity. 2024 Nov 15:S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012. Online ahead of print. Immunity. 2024. PMID: 39571574 Free article.
Immune Response to SARS-CoV-2 XBB.1.5 and JN.1 Variants Following XBB.1.5 Booster Vaccination in Liver Transplant Recipients.
von der Schulenburg P, Behrens GMN, Hoffmann M, Linke A, Nehlmeier I, Kempf AM, Stankov M, Lütgehetmann M, Jahnke-Triankowski J, Addo MM, Fischer L, Lohse AW, Pöhlmann S, Schulze Zur Wiesch J, Sterneck M. von der Schulenburg P, et al. Among authors: fischer l. Viruses. 2024 Dec 19;16(12):1942. doi: 10.3390/v16121942. Viruses. 2024. PMID: 39772248
Effects of chemoradiotherapy on surface PD-L1 expression in esophageal cancer and its implications for immunotherapy.
Hampe L, Küffer S, Niemeier T, Scheele NC, Hampe LZ, Riedl AL, Fischer LA, Ziegler DA, Leu M, Dröge LH, König A, Ghadimi M, Braulke F, Rieken S, Bohnenberger H, El Shafie RA. Hampe L, et al. Among authors: fischer la. Front Immunol. 2024 Dec 23;15:1509051. doi: 10.3389/fimmu.2024.1509051. eCollection 2024. Front Immunol. 2024. PMID: 39763660 Free PMC article.
Cross-Sectional Analyses to Assess the Clinical Safety and Effectiveness of Bisoprolol in Patients With Non-obstructive Coronary Artery Disease Who Underwent Percutaneous Coronary Intervention: A Post-hoc Analysis.
Pinto B, Kulkarni GR, Kumar S, Deb A, Fischer L, Khandelwal A, Korukonda KR, Nair R. Pinto B, et al. Among authors: fischer l. Cureus. 2024 Dec 3;16(12):e75021. doi: 10.7759/cureus.75021. eCollection 2024 Dec. Cureus. 2024. PMID: 39749095 Free PMC article.
The phenomenon of despair in patients with depression.
Mavrogiorgou P, Fischer L, Bürgy M, Juckel G. Mavrogiorgou P, et al. Among authors: fischer l. J Psychiatr Res. 2024 Dec 24;181:648-652. doi: 10.1016/j.jpsychires.2024.12.021. Online ahead of print. J Psychiatr Res. 2024. PMID: 39742795 Free article.
The translocator protein 18 kDa (TSPO) ligand etifoxine in an animal model of anxiety: Line- and sex-dependent effects on emotionality, stress reactivity, spine density, oxytocin receptors, steroids, and microbiome composition.
Fischer L, Paschke B, Gareis F, Schumacher M, Liere P, Hiergeist A, Gessner A, Rupprecht R, Neumann ID, Bosch OJ. Fischer L, et al. Neuropharmacology. 2024 Dec 24;266:110282. doi: 10.1016/j.neuropharm.2024.110282. Online ahead of print. Neuropharmacology. 2024. PMID: 39725124 Free article.
1,849 results