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Utility of polygenic risk scores in UK cancer screening: a modelling analysis.
Huntley C, Torr B, Sud A, Rowlands CF, Way R, Snape K, Hanson H, Swanton C, Broggio J, Lucassen A, McCartney M, Houlston RS, Hingorani AD, Jones ME, Turnbull C. Huntley C, et al. Among authors: hingorani ad. Lancet Oncol. 2023 Jun;24(6):658-668. doi: 10.1016/S1470-2045(23)00156-0. Epub 2023 May 10. Lancet Oncol. 2023. PMID: 37178708 Free article. Review.
NMR metabolomic modelling of age and lifespan: a multi-cohort analysis.
Lau CE, Manou M, Markozannes G, Ala-Korpela M, Ben-Shlomo Y, Chaturvedi N, Engmann J, Gentry-Maharaj A, Herzig KH, Hingorani A, Järvelin MR, Kähönen M, Kivimäki M, Lehtimäki T, Marttila S, Menon U, Munroe PB, Palaniswamy S, Providencia R, Raitakari O, Schmidt F, Sebert S, Wong A, Vineis P, Tzoulaki I, Robinson O. Lau CE, et al. medRxiv [Preprint]. 2023 Nov 8:2023.11.07.23298200. doi: 10.1101/2023.11.07.23298200. medRxiv. 2023. Update in: Aging Cell. 2024 Jul;23(7):e14164. doi: 10.1111/acel.14164 PMID: 37986811 Free PMC article. Updated. Preprint.
Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study.
Hamilton FW, Thomas M, Arnold D, Palmer T, Moran E, Mentzer AJ, Maskell N, Baillie K, Summers C, Hingorani A, MacGowan A, Khandaker GM, Mitchell R, Davey Smith G, Ghazal P, Timpson NJ. Hamilton FW, et al. PLoS Med. 2023 Jan 30;20(1):e1004174. doi: 10.1371/journal.pmed.1004174. eCollection 2023 Jan. PLoS Med. 2023. PMID: 36716318 Free PMC article.
Prioritising genetic findings for drug target identification and validation.
Hukerikar N, Hingorani AD, Asselbergs FW, Finan C, Schmidt AF. Hukerikar N, et al. Among authors: hingorani ad. Atherosclerosis. 2024 Mar;390:117462. doi: 10.1016/j.atherosclerosis.2024.117462. Epub 2024 Jan 26. Atherosclerosis. 2024. PMID: 38325120 Free article. Review.
Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders.
Schmidt AF, Finan C, Chopade S, Ellmerich S, Rossor MN, Hingorani AD, Pepys MB. Schmidt AF, et al. Among authors: hingorani ad. medRxiv [Preprint]. 2023 Aug 16:2023.08.15.23293564. doi: 10.1101/2023.08.15.23293564. medRxiv. 2023. Update in: Open Biol. 2024 Jul;14(7):230419. doi: 10.1098/rsob.230419 PMID: 37645746 Free PMC article. Updated. Preprint.
322 results