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Page 1
Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells.
Soethoudt M, Stolze SC, Westphal MV, van Stralen L, Martella A, van Rooden EJ, Guba W, Varga ZV, Deng H, van Kasteren SI, Grether U, IJzerman AP, Pacher P, Carreira EM, Overkleeft HS, Ioan-Facsinay A, Heitman LH, van der Stelt M. Soethoudt M, et al. Among authors: grether u. J Am Chem Soc. 2018 May 16;140(19):6067-6075. doi: 10.1021/jacs.7b11281. Epub 2018 Feb 16. J Am Chem Soc. 2018. PMID: 29420021 Free PMC article.
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists.
Kosar M, Sarott RC, Sykes DA, Viray AEG, Vitale RM, Tomašević N, Li X, Ganzoni RLZ, Kicin B, Reichert L, Patej KJ, Gómez-Bouzó U, Guba W, McCormick PJ, Hua T, Gruber CW, Veprintsev DB, Frank JA, Grether U, Carreira EM. Kosar M, et al. Among authors: grether u. ACS Cent Sci. 2024 Mar 11;10(5):956-968. doi: 10.1021/acscentsci.3c01461. eCollection 2024 May 22. ACS Cent Sci. 2024. PMID: 38799662 Free PMC article.
Editorial: Therapeutic potential of the cannabinoid CB2 receptor.
Smoum R, Grether U, Karsak M, Vernall AJ, Park F, Hillard CJ, Pacher P. Smoum R, et al. Among authors: grether u. Front Pharmacol. 2022 Oct 7;13:1039564. doi: 10.3389/fphar.2022.1039564. eCollection 2022. Front Pharmacol. 2022. PMID: 36278235 Free PMC article. No abstract available.
A highly potent, orally bioavailable pyrazole-derived cannabinoid CB2 receptor-selective full agonist for in vivo studies.
Chicca A, Batora D, Ullmer C, Caruso A, Fingerle J, Hartung T, Degen R, Müller M, Grether U, Pacher P, Gertsch J. Chicca A, et al. Among authors: grether u. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311. doi: 10.1101/2024.04.26.591311. bioRxiv. 2024. Update in: ACS Pharmacol Transl Sci. 2024 Jul 09;7(8):2424-2438. doi: 10.1021/acsptsci.4c00269 PMID: 38903103 Free PMC article. Updated. Preprint.
An oxidation-labile traceless linker for solid-phase synthesis.
Stieber F, Grether U, Waldmann H. Stieber F, et al. Among authors: grether u. Angew Chem Int Ed Engl. 1999;38(8):1073-7. doi: 10.1002/(SICI)1521-3773(19990419)38:8<1073::AID-ANIE1073>3.0.CO;2-Y. Angew Chem Int Ed Engl. 1999. PMID: 25138498
76 results