Clarke M - Search Results

1

Reversal of MYB-dependent suppression of MAFB expression overrides leukaemia phenotype in MLL-rearranged AML.

Negri A, Ward C, Bucci A, D'Angelo G, Cauchy P, Radesco A, Ventura AB, Walton DS, Clarke M, Mandriani B, Pappagallo SA, Mondelli P, Liao K, Gargano G, Zaccaria GM, Viggiano L, Lasorsa FM, Ahmed A, Di Molfetta D, Fiermonte G, Cives M, Guarini A, Vegliante MC, Ciavarella S, Frampton J, Volpe G. Negri A, et al. Among authors: clarke m. Cell Death Dis. 2023 Nov 23;14(11):763. doi: 10.1038/s41419-023-06276-z. Cell Death Dis. 2023. PMID: 37996430 Free PMC article.

2

Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis.

García P, Clarke M, Vegiopoulos A, Berlanga O, Camelo A, Lorvellec M, Frampton J. García P, et al. Among authors: clarke m. EMBO J. 2009 May 20;28(10):1492-504. doi: 10.1038/emboj.2009.97. Epub 2009 Apr 9. EMBO J. 2009. PMID: 19360001 Free PMC article.

3

MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.

Clarke M, Dumon S, Ward C, Jäger R, Freeman S, Dawood B, Sheriff L, Lorvellec M, Kralovics R, Frampton J, García P. Clarke M, et al. Leukemia. 2013 Mar;27(3):661-70. doi: 10.1038/leu.2012.241. Epub 2012 Aug 22. Leukemia. 2013. PMID: 22910183 Free PMC article.

4

Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.

Volpe G, Clarke M, Garcìa P, Walton DS, Vegiopoulos A, Del Pozzo W, O'Neill LP, Frampton J, Dumon S. Volpe G, et al. Among authors: clarke m. PLoS One. 2015 Sep 18;10(9):e0138257. doi: 10.1371/journal.pone.0138257. eCollection 2015. PLoS One. 2015. PMID: 26382271 Free PMC article.

5

Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.

Clarke M, Volpe G, Sheriff L, Walton D, Ward C, Wei W, Dumon S, García P, Frampton J. Clarke M, et al. Leukemia. 2017 Apr;31(4):957-966. doi: 10.1038/leu.2016.289. Epub 2016 Oct 17. Leukemia. 2017. PMID: 27748374 Free PMC article.

6

Dependence on Myb expression is attenuated in myeloid leukaemia with N-terminal CEBPA mutations.

Volpe G, Cauchy P, Walton DS, Ward C, Blakemore D, Bayley R, Clarke ML, Schmidt L, Nerlov C, Garcia P, Dumon S, Grebien F, Frampton J. Volpe G, et al. Life Sci Alliance. 2019 Mar 15;2(2):e201800207. doi: 10.26508/lsa.201800207. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30877232 Free PMC article.

7

MYB insufficiency disrupts proteostasis in hematopoietic stem cells, leading to age-related neoplasia.

Clarke ML, Lemma RB, Walton DS, Volpe G, Noyvert B, Gabrielsen OS, Frampton J. Clarke ML, et al. Blood. 2023 Apr 13;141(15):1858-1870. doi: 10.1182/blood.2022019138. Blood. 2023. PMID: 36603185 Free PMC article.

8

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.

Varadinkova S, Oralova V, Clarke M, Frampton J, Knopfova L, Lesot H, Bartos P, Matalova E. Varadinkova S, et al. Among authors: clarke m. Front Cell Dev Biol. 2023 Aug 28;11:1168866. doi: 10.3389/fcell.2023.1168866. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37701782 Free PMC article.

9

MYB as a Critical Transcription Factor and Potential Therapeutic Target in AML.

Clarke ML, Gabrielsen OS, Frampton J. Clarke ML, et al. Adv Exp Med Biol. 2024;1459:341-358. doi: 10.1007/978-3-031-62731-6_15. Adv Exp Med Biol. 2024. PMID: 39017851 Review.

10

Basic Science and Pathogenesis.

Ho WHD, Djomehri SI, Alford VM, Chen EY, Reinitz F, Gottlieb S, Igboabuchi FI, Chung GY, Fernandez D, Montabana E, Singal B, Qi Z, Kuo AH, Qian D, Clarke MF. Ho WHD, et al. Among authors: clarke mf. Alzheimers Dement. 2024 Dec;20 Suppl 1:e093300. doi: 10.1002/alz.093300. Alzheimers Dement. 2024. PMID: 39750542

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