Oo A - Search Results

1

Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells.

Valeri E, Unali G, Piras F, Abou-Alezz M, Pais G, Benedicenti F, Lidonnici MR, Cuccovillo I, Castiglioni I, Arévalo S, Spinozzi G, Merelli I, Behrendt R, Oo A, Kim B, Landau NR, Ferrari G, Montini E, Kajaste-Rudnitski A. Valeri E, et al. Among authors: oo a. Mol Ther. 2024 Jan 3;32(1):124-139. doi: 10.1016/j.ymthe.2023.11.020. Epub 2023 Nov 20. Mol Ther. 2024. PMID: 37990494 Free PMC article.

2

Viral protein X reduces the incorporation of mutagenic noncanonical rNTPs during lentivirus reverse transcription in macrophages.

Oo A, Kim DH, Schinazi RF, Kim B. Oo A, et al. J Biol Chem. 2020 Jan 10;295(2):657-666. doi: 10.1074/jbc.RA119.011466. Epub 2019 Dec 5. J Biol Chem. 2020. PMID: 31806704 Free PMC article.

3

Mechanistic Interplay between HIV-1 Reverse Transcriptase Enzyme Kinetics and Host SAMHD1 Protein: Viral Myeloid-Cell Tropism and Genomic Mutagenesis.

Bowen NE, Oo A, Kim B. Bowen NE, et al. Among authors: oo a. Viruses. 2022 Jul 26;14(8):1622. doi: 10.3390/v14081622. Viruses. 2022. PMID: 35893688 Free PMC article. Review.

4

Biochemical simulation of mutation synthesis and repair during SARS-CoV-2 RNA polymerization.

Oo A, Chen Z, Cao D, Cho YJ, Liang B, Schinazi RF, Kim B. Oo A, et al. Virology. 2024 Dec;600:110255. doi: 10.1016/j.virol.2024.110255. Epub 2024 Oct 1. Virology. 2024. PMID: 39366027 Free article.

5

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels.

Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. Among authors: oo a. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554731. doi: 10.1101/2023.08.24.554731. bioRxiv. 2023. Update in: mBio. 2023 Oct 31;14(5):e0225223. doi: 10.1128/mbio.02252-23 PMID: 37662193 Free PMC article. Updated. Preprint.

6

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels.

Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. Among authors: oo a. mBio. 2023 Oct 31;14(5):e0225223. doi: 10.1128/mbio.02252-23. Epub 2023 Oct 6. mBio. 2023. PMID: 37800914 Free PMC article.

7

Nucleotide Analogues Bearing a C2' or C3'-Stereogenic All-Carbon Quaternary Center as SARS-CoV-2 RdRp Inhibitors.

Manchoju A, Zelli R, Wang G, Eymard C, Oo A, Nemer M, Prévost M, Kim B, Guindon Y. Manchoju A, et al. Among authors: oo a. Molecules. 2022 Jan 17;27(2):564. doi: 10.3390/molecules27020564. Molecules. 2022. PMID: 35056878 Free PMC article.

8

Elimination of Aicardi-Goutières syndrome protein SAMHD1 activates cellular innate immunity and suppresses SARS-CoV-2 replication.

Oo A, Zandi K, Shepard C, Bassit LC, Musall K, Goh SL, Cho YJ, Kim DH, Schinazi RF, Kim B. Oo A, et al. J Biol Chem. 2022 Mar;298(3):101635. doi: 10.1016/j.jbc.2022.101635. Epub 2022 Jan 25. J Biol Chem. 2022. PMID: 35085552 Free PMC article.

9

Repurposing Nucleoside Analogs for Human Coronaviruses.

Zandi K, Amblard F, Musall K, Downs-Bowen J, Kleinbard R, Oo A, Cao D, Liang B, Russell OO, McBrayer T, Bassit L, Kim B, Schinazi RF. Zandi K, et al. Among authors: oo a. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01652-20. doi: 10.1128/AAC.01652-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33122172 Free PMC article.

10

Novel Insights into the Molecular Regulation of Ribonucleotide Reductase in Adrenocortical Carcinoma Treatment.

Bothou C, Sharma A, Oo A, Kim B, Perge P, Igaz P, Ronchi CL, Shapiro I, Hantel C. Bothou C, et al. Among authors: oo a. Cancers (Basel). 2021 Aug 20;13(16):4200. doi: 10.3390/cancers13164200. Cancers (Basel). 2021. PMID: 34439352 Free PMC article.

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