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Systemic treatment with a selective TNFR2 agonist alters the central and peripheral immune responses and transiently improves functional outcome after experimental ischemic stroke.
Thougaard E, Nielsen PV, Forsberg A, Phuong V, Velasco AM, Wlodarczyk A, Wajant H, Lang I, Mikkelsen JD, Clausen BH, Brambilla R, Lambertsen KL. Thougaard E, et al. Among authors: brambilla r. J Neuroimmunol. 2023 Dec 15;385:578246. doi: 10.1016/j.jneuroim.2023.578246. Epub 2023 Nov 17. J Neuroimmunol. 2023. PMID: 37988839 Free article.
Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders.
Gao H, Di J, Clausen BH, Wang N, Zhu X, Zhao T, Chang Y, Pang M, Yang Y, He R, Wang Y, Zhang L, Liu B, Qiu W, Lambertsen KL, Brambilla R, Rong L. Gao H, et al. Among authors: brambilla r. Cell Rep. 2023 Jun 27;42(6):112629. doi: 10.1016/j.celrep.2023.112629. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37289590 Free article.
TNFR2 signaling in oligodendrocyte precursor cells suppresses their immune-inflammatory function and detrimental microglia activation in CNS demyelinating disease.
Desu HL, Thougaard E, Carney BN, Illiano P, Plastini MJ, Florimon Y, Mini A, Guastucci C, Kang B, Lee JK, Lambertsen KL, Brambilla R. Desu HL, et al. Among authors: brambilla r. Brain Behav Immun. 2025 Jan;123:81-98. doi: 10.1016/j.bbi.2024.09.002. Epub 2024 Sep 5. Brain Behav Immun. 2025. PMID: 39243989
Small-molecule modulators of tumor necrosis factor signaling.
Chédotal H, Narayanan D, Povlsen K, Gotfredsen CH, Brambilla R, Gajhede M, Bach A, Clausen MH. Chédotal H, et al. Among authors: brambilla r. Drug Discov Today. 2023 Jun;28(6):103575. doi: 10.1016/j.drudis.2023.103575. Epub 2023 Mar 30. Drug Discov Today. 2023. PMID: 37003513 Free article. Review.
Increased activity of IRE1 improves the clinical presentation of EAE.
Bracchi-Ricard V, Nguyen K, Ricci D, Gaudette B, Henao-Meija J, Brambilla R, Martynyuk T, Gidalevitz T, Allman D, Bethea JR, Argon Y. Bracchi-Ricard V, et al. Among authors: brambilla r. bioRxiv [Preprint]. 2023 Apr 20:2023.04.19.537391. doi: 10.1101/2023.04.19.537391. bioRxiv. 2023. Update in: FASEB J. 2023 Dec;37(12):e23283. doi: 10.1096/fj.202300769RR PMID: 37131811 Free PMC article. Updated. Preprint.
Increased activity of IRE1 improves the clinical presentation of EAE.
Bracchi-Ricard V, Nguyen K, Ricci D, Gaudette B, Henao-Mejia J, Brambilla R, Martynyuk T, Gidalevitz T, Allman D, Bethea JR, Argon Y. Bracchi-Ricard V, et al. Among authors: brambilla r. FASEB J. 2023 Dec;37(12):e23283. doi: 10.1096/fj.202300769RR. FASEB J. 2023. PMID: 37983957 Free PMC article.
Chorioamnionitis accelerates granule cell and oligodendrocyte maturation in the cerebellum of preterm nonhuman primates.
Newman J, Tong X, Tan A, Yeasky T, De Paiva VN, Presicce P, Kannan PS, Williams K, Damianos A, Tamase Newsam M, Benny MK, Wu S, Young KC, Miller LA, Kallapur SG, Chougnet CA, Jobe AH, Brambilla R, Schmidt AF. Newman J, et al. Among authors: brambilla r. J Neuroinflammation. 2024 Jan 10;21(1):16. doi: 10.1186/s12974-024-03012-y. J Neuroinflammation. 2024. PMID: 38200558 Free PMC article.
258 results