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Targeting Polymerase Theta (POLθ) for Cancer Therapy.
Patterson-Fortin J, D'Andrea AD. Patterson-Fortin J, et al. Among authors: d andrea ad. Cancer Treat Res. 2023;186:285-298. doi: 10.1007/978-3-031-30065-3_15. Cancer Treat Res. 2023. PMID: 37978141 Review.
STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition.
Zhou J, Nie RC, He ZP, Cai XX, Chen JW, Lin WP, Yin YX, Xiang ZC, Zhu TC, Xie JJ, Zhang YC, Wang X, Lin P, Xie D, D'Andrea AD, Cai MY. Zhou J, et al. Among authors: d andrea ad. Adv Sci (Weinh). 2023 Dec;10(36):e2302494. doi: 10.1002/advs.202302494. Epub 2023 Nov 20. Adv Sci (Weinh). 2023. PMID: 37985839 Free PMC article.
DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology.
Rahman R, Shi DD, Reitman ZJ, Hamerlik P, de Groot JF, Haas-Kogan DA, D'Andrea AD, Sulman EP, Tanner K, Agar NYR, Sarkaria JN, Tinkle CL, Bindra RS, Mehta MP, Wen PY. Rahman R, et al. Among authors: d andrea ad. Neuro Oncol. 2024 Aug 5;26(8):1367-1387. doi: 10.1093/neuonc/noae072. Neuro Oncol. 2024. PMID: 38770568 Review.
Fork restart: unloading FANCD2 to travel ahead.
Iyer DR, D'Andrea AD. Iyer DR, et al. Mol Cell. 2023 Oct 19;83(20):3590-3592. doi: 10.1016/j.molcel.2023.09.027. Mol Cell. 2023. PMID: 37863027 Free article.
Transforming ovarian cancer care by targeting minimal residual disease.
Jazaeri AA, Grisham R, Knisely A, Spranger S, Zamarin D, Hillman RT, Lawson BC, Burns KH, Lee S, Westin SN, Moiso E, Williams MJ, Bardhan NM, Pisanic T, Matulonis U, Weigelt B, Shih I, Konstantinopoulos PA, Gaillard S, Wang L, Aghajanian C, D'Andrea AD, Hammond P, Shah S, Wucherpfennig KW, Lu KH. Jazaeri AA, et al. Med. 2023 Nov 10;4(11):755-760. doi: 10.1016/j.medj.2023.08.004. Med. 2023. PMID: 37951209 Free PMC article.
PARG inhibitor sensitivity correlates with accumulation of single-stranded DNA gaps in preclinical models of ovarian cancer.
Ravindranathan R, Somuncu O, da Costa AABA, Mukkavalli S, Lamarre BP, Nguyen H, Grochala C, Jiao Y, Liu J, Kochupurakkal B, Parmar K, Shapiro GI, D'Andrea AD. Ravindranathan R, et al. Among authors: d andrea ad. Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2413954121. doi: 10.1073/pnas.2413954121. Epub 2024 Nov 15. Proc Natl Acad Sci U S A. 2024. PMID: 39546575
Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression.
Diossy M, Tisza V, Li H, Sahgal P, Zhou J, Sztupinszki Z, Young D, Nousome D, Kuo C, Jiang J, Chen Y, Ebner R, Sesterhenn IA, Moncur JT, Chesnut GT, Petrovics G, Klus GT, Valcz G, Nuzzo PV, Ribli D, Börcsök J, Prosz A, Krzystanek M, Ried T, Szuts D, Rizwan K, Kaochar S, Pathania S, D'Andrea AD, Csabai I, Srivastava S, Freedman ML, Dobi A, Spisak S, Szallasi Z. Diossy M, et al. Among authors: d andrea ad. NPJ Precis Oncol. 2024 Sep 19;8(1):208. doi: 10.1038/s41698-024-00705-8. NPJ Precis Oncol. 2024. PMID: 39294262 Free PMC article.
CDK5-cyclin B1 regulates mitotic fidelity.
Zheng XF, Sarkar A, Lotana H, Syed A, Nguyen H, Ivey RG, Kennedy JJ, Whiteaker JR, Tomasik B, Huang K, Li F, D'Andrea AD, Paulovich AG, Shah K, Spektor A, Chowdhury D. Zheng XF, et al. Among authors: d andrea ad. Nature. 2024 Sep;633(8031):932-940. doi: 10.1038/s41586-024-07888-x. Epub 2024 Sep 4. Nature. 2024. PMID: 39232161
The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway.
Harada N, Asada S, Jiang L, Nguyen H, Moreau L, Marina RJ, Adelman K, Iyer DR, D'Andrea AD. Harada N, et al. Among authors: d andrea ad. Mol Cell. 2024 Jul 25;84(14):2618-2633.e10. doi: 10.1016/j.molcel.2024.06.031. Epub 2024 Jul 17. Mol Cell. 2024. PMID: 39025073 Free PMC article.
Single-Stranded DNA Gap Accumulation Is a Functional Biomarker for USP1 Inhibitor Sensitivity.
da Costa AA, Somuncu O, Ravindranathan R, Mukkavalli S, Martignetti DB, Nguyen H, Jiao Y, Lamarre BP, Sadatrezaei G, Moreau L, Liu J, Iyer DR, Lazaro JB, Shapiro GI, Parmar K, D'Andrea AD. da Costa AA, et al. Among authors: d andrea ad. Cancer Res. 2024 Oct 15;84(20):3435-3446. doi: 10.1158/0008-5472.CAN-23-4007. Cancer Res. 2024. PMID: 38885312 Free PMC article.
285 results