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Ex-vivo rectal tissue infection with HIV-1 to assess time to protection following oral preexposure prophylaxis with tenofovir disoproxil/emtricitabine.
Chawki S, Goldwirt L, Mouhebb ME, Gabassi A, Taouk M, Bichard I, Loze B, Amara A, Brand R, Siegel A, McGowan I, Costagliola D, Assoumou L, Molina JM, Delaugerre C; ANRS PREVENIR Study group. Chawki S, et al. Among authors: siegel a. AIDS. 2024 Mar 15;38(4):455-464. doi: 10.1097/QAD.0000000000003789. Epub 2023 Nov 22. AIDS. 2024. PMID: 37976073 Free PMC article.
A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study).
McGowan IM, Chawki S, Hendrix CW, Anton PA, Marzinke MA, Brand RM, Engstrom JC, Rohan LC, Abebe KZ, Richardson-Harman N, Siegel A, Reinhart A, Steytler J, Stall R, Spiegel H, Chen B, Achilles SL, Jacobson CE, Khanukova E, Cranston RD. McGowan IM, et al. Among authors: siegel a. AIDS Res Hum Retroviruses. 2022 Apr;38(4):269-278. doi: 10.1089/AID.2021.0096. Epub 2021 Sep 14. AIDS Res Hum Retroviruses. 2022. PMID: 34384282 Free PMC article. Clinical Trial.
A Multiple Dose Phase 1 Assessment of Rilpivirine Long Acting in a Model of Preexposure Prophylaxis Against HIV.
Cranston RD, Dezzutti CS, Siegel A, Engstrom J, Shetler C, Richardson-Harman N, Abebe KZ, Back D, Else L, Egan D, Khoo S, Egan JE, Stall R, Williams P, Brand RM, Parikh UM, McGowan I. Cranston RD, et al. Among authors: siegel a. AIDS Res Hum Retroviruses. 2019 Sep;35(9):794-804. doi: 10.1089/AID.2018.0265. Epub 2019 Jul 16. AIDS Res Hum Retroviruses. 2019. PMID: 31146534 Clinical Trial.
Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells.
Brand RM, Moore BA, Zyhowski A, Siegel A, Uttam S, Metter EJ, Engstrom J, Brand RE, Biswas N, Whitcomb DC, Binion DG, Schwartz M, McGowan I. Brand RM, et al. Among authors: siegel a. Am J Physiol Gastrointest Liver Physiol. 2021 Mar 1;320(3):G396-G410. doi: 10.1152/ajpgi.00383.2020. Epub 2020 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33355506 Free PMC article.
Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women.
McGowan I, Cranston RD, Mayer KH, Febo I, Duffill K, Siegel A, Engstrom JC, Nikiforov A, Park SY, Brand RM, Jacobson C, Giguere R, Dolezal C, Frasca T, Leu CS, Schwartz JL, Carballo-Diéguez A. McGowan I, et al. Among authors: siegel a. PLoS One. 2016 Jun 30;11(6):e0158310. doi: 10.1371/journal.pone.0158310. eCollection 2016. PLoS One. 2016. PMID: 27362788 Free PMC article. Clinical Trial.
Prevalence and determinants of anal human papillomavirus infection in men who have sex with men and transgender women.
Cranston RD, Carballo-Diéguez A, Gundacker H, Richardson BA, Giguere R, Dolezal C, Siegel A, KunjaraNaAyudhya RP, Gomez K, Piper JM, Lama JR, McGowan I; MTN-017 Protocol Team. Cranston RD, et al. Among authors: siegel a. Int J STD AIDS. 2019 Feb;30(2):154-162. doi: 10.1177/0956462418797864. Epub 2018 Oct 18. Int J STD AIDS. 2019. PMID: 30336747 Free PMC article.
1,248 results