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PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.
Sachan V, Le Dévéhat M, Roubtsova A, Essalmani R, Laurendeau JF, Garçon D, Susan-Resiga D, Duval S, Mikaeeli S, Hamelin J, Evagelidis A, Chong M, Paré G, Chernetsova E, Gao ZH, Robillard I, Ruiz M, Trinh VQ, Estall JL, Faraj M, Austin RC, Sauvageau M, Prat A, Kiss RS, Seidah NG. Sachan V, et al. Among authors: seidah ng. Metabolism. 2024 Jan;150:155736. doi: 10.1016/j.metabol.2023.155736. Epub 2023 Nov 13. Metabolism. 2024. PMID: 37967646
Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels.
Fruchart Gaillard C, Ouadda ABD, Ciccone L, Girard E, Mikaeeli S, Evagelidis A, Le Dévéhat M, Susan-Resiga D, Lajeunesse EC, Nozach H, Ramos OHP, Thureau A, Legrand P, Prat A, Dive V, Seidah NG. Fruchart Gaillard C, et al. Among authors: seidah ng. Mol Metab. 2023 Jan;67:101662. doi: 10.1016/j.molmet.2022.101662. Epub 2022 Dec 22. Mol Metab. 2023. PMID: 36566984 Free PMC article.
Surface LDLR is a major receptor for lipoprotein(a) clearance in male mice lacking PCSK9.
Roubtsova A, Scipione CA, Garçon D, Boffa MB, Seidah NG, Koschinsky ML, Prat A. Roubtsova A, et al. Among authors: seidah ng. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Apr;1868(4):159288. doi: 10.1016/j.bbalip.2023.159288. Epub 2023 Jan 25. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 36708961 No abstract available.
Corrigendum to "PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease" [Metabolism Volume 150, January 2024, 155736, PMID: 7967646].
Sachan V, LeDévéhat M, Roubtsova A, Essalmani R, Laurendeau JF, Garçon D, Susan-Sesiga D, Duval S, Mikaeeli S, Hamelin J, Evagelidis A, Chong M, Paré G, Chernetsova E, Gao ZH, Robillard I, Ruiz M, Trinh VQ, Estall JL, Faraj M, Austin RC, Sauvageau M, Prat A, Kiss RS, Seidah NG. Sachan V, et al. Among authors: seidah ng. Metabolism. 2024 Dec;161:156032. doi: 10.1016/j.metabol.2024.156032. Epub 2024 Sep 19. Metabolism. 2024. PMID: 39298889 No abstract available.
GDF10 is a negative regulator of vascular calcification.
Platko K, Gyulay G, Lebeau PF, MacDonald ME, Lynn EG, Byun JH, Igdoura SA, Holden RM, Roubtsova A, Seidah NG, Krepinsky JC, Austin RC. Platko K, et al. Among authors: seidah ng. J Biol Chem. 2024 Nov;300(11):107805. doi: 10.1016/j.jbc.2024.107805. Epub 2024 Sep 21. J Biol Chem. 2024. PMID: 39307303 Free PMC article.
PCSK9 in metabolism and diseases.
Ajoolabady A, Pratico D, Mazidi M, Davies IG, Lip GYH, Seidah N, Libby P, Kroemer G, Ren J. Ajoolabady A, et al. Metabolism. 2025 Feb;163:156064. doi: 10.1016/j.metabol.2024.156064. Epub 2024 Nov 14. Metabolism. 2025. PMID: 39547595 Review.
651 results