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TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.
Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. Liu G, et al. Among authors: murakami y. Nat Commun. 2023 Nov 14;14(1):7349. doi: 10.1038/s41467-023-42913-z. Nat Commun. 2023. PMID: 37963864 Free PMC article.
Guanosine and its modified derivatives are endogenous ligands for TLR7.
Shibata T, Ohto U, Nomura S, Kibata K, Motoi Y, Zhang Y, Murakami Y, Fukui R, Ishimoto T, Sano S, Ito T, Shimizu T, Miyake K. Shibata T, et al. Among authors: murakami y. Int Immunol. 2016 May;28(5):211-22. doi: 10.1093/intimm/dxv062. Epub 2015 Oct 20. Int Immunol. 2016. PMID: 26489884 Free PMC article.
C4b-binding protein negatively regulates TLR4/MD-2 response but not TLR3 response.
Morita N, Yamazaki T, Murakami Y, Fukui R, Yamai I, Ichimonji I, Nakashima A, Nagaoka F, Takagi H, Miyake K, Akashi-Takamura S. Morita N, et al. Among authors: murakami y. FEBS Lett. 2017 Jun;591(12):1732-1741. doi: 10.1002/1873-3468.12693. Epub 2017 Jun 12. FEBS Lett. 2017. PMID: 28542817 Free article.
Mechanisms controlling nucleic acid-sensing Toll-like receptors.
Miyake K, Shibata T, Ohto U, Shimizu T, Saitoh SI, Fukui R, Murakami Y. Miyake K, et al. Among authors: murakami y. Int Immunol. 2018 Mar 8;30(2):43-51. doi: 10.1093/intimm/dxy016. Int Immunol. 2018. PMID: 29452403 Review.
Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.
Sato R, Kato A, Chimura T, Saitoh SI, Shibata T, Murakami Y, Fukui R, Liu K, Zhang Y, Arii J, Sun-Wada GH, Wada Y, Ikenoue T, Barber GN, Manabe T, Kawaguchi Y, Miyake K. Sato R, et al. Among authors: murakami y. Nat Immunol. 2018 Oct;19(10):1071-1082. doi: 10.1038/s41590-018-0203-2. Epub 2018 Sep 10. Nat Immunol. 2018. PMID: 30201994
4,149 results