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Page 1
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics.
Lee HM, Wright WC, Pan M, Low J, Currier D, Fang J, Singh S, Nance S, Delahunty I, Kim Y, Chapple RH, Zhang Y, Liu X, Steele JA, Qi J, Pruett-Miller SM, Easton J, Chen T, Yang J, Durbin AD, Geeleher P. Lee HM, et al. Among authors: steele ja. Nat Commun. 2023 Nov 13;14(1):7332. doi: 10.1038/s41467-023-43134-0. Nat Commun. 2023. PMID: 37957169 Free PMC article.
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.
Karki R, Lee S, Mall R, Pandian N, Wang Y, Sharma BR, Malireddi RS, Yang D, Trifkovic S, Steele JA, Connelly JP, Vishwanath G, Sasikala M, Reddy DN, Vogel P, Pruett-Miller SM, Webby R, Jonsson CB, Kanneganti TD. Karki R, et al. Among authors: steele ja. Sci Immunol. 2022 Aug 26;7(74):eabo6294. doi: 10.1126/sciimmunol.abo6294. Epub 2022 Aug 26. Sci Immunol. 2022. PMID: 35587515 Free PMC article.
Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.
Fang J, Singh S, Cheng C, Natarajan S, Sheppard H, Abu-Zaid A, Durbin AD, Lee HW, Wu Q, Steele J, Connelly JP, Jin H, Chen W, Fan Y, Pruett-Miller SM, Rehg JE, Koo SC, Santiago T, Emmons J, Cairo S, Wang R, Glazer ES, Murphy AJ, Chen T, Davidoff AM, Armengol C, Easton J, Chen X, Yang J. Fang J, et al. Nat Commun. 2023 Jul 6;14(1):4003. doi: 10.1038/s41467-023-39717-6. Nat Commun. 2023. PMID: 37414763 Free PMC article.
RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity.
Singh S, Fang J, Jin H, Van de Velde LA, Wu Q, Cortes A, Morton CL, Woolard MA, Quarni W, Steele JA, Connelly JP, He L, Thorne R, Turner G, Confer T, Johnson M, Caufield WV, Freeman BB, Lockey T, Pruett-Miller SM, Wang R, Davidoff AM, Thomas PG, Yang J. Singh S, et al. Among authors: steele ja. bioRxiv [Preprint]. 2024 Mar 25:2024.03.21.586157. doi: 10.1101/2024.03.21.586157. bioRxiv. 2024. PMID: 38585889 Free PMC article. Preprint.
Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid.
Pan M, Zhang Y, Wright WC, Liu X, Passaia B, Currier D, Low J, Chapple RH, Steele JA, Connelly JP, Lu M, Lee HM, Loughran AJ, Yang L, Abraham BJ, Pruett-Miller SM, Freeman B, Campbell GE, Dyer MA, Chen T, Stewart E, Koo S, Sheppard H, Easton J, Geeleher P. Pan M, et al. Among authors: steele ja. bioRxiv [Preprint]. 2024 May 14:2024.05.09.593394. doi: 10.1101/2024.05.09.593394. bioRxiv. 2024. PMID: 38798584 Free PMC article. Preprint.
The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells.
Fang J, Singh S, Wells B, Wu Q, Jin H, Janke LJ, Wan S, Steele JA, Connelly JP, Murphy AJ, Wang R, Davidoff AM, Ashcroft M, Pruett-Miller SM, Yang J. Fang J, et al. Among authors: steele ja. Res Sq [Preprint]. 2024 Dec 20:rs.3.rs-4390765. doi: 10.21203/rs.3.rs-4390765/v1. Res Sq. 2024. PMID: 38853928 Free PMC article. Preprint.
The influence of urbanization and water reclamation plants on fecal indicator bacteria and antibiotic resistance in the Los Angeles River watershed: A case study with complementary monitoring methods.
Callejas IA, Kong Y, Osborn K, Hung WC, Cira M, Cason T, Sloane A, Shenkiryk A, Masikip A, Singh A, Jones A, Steele JA, Jay JA. Callejas IA, et al. Among authors: steele ja. Sci Total Environ. 2024 Dec 20;957:177577. doi: 10.1016/j.scitotenv.2024.177577. Epub 2024 Nov 21. Sci Total Environ. 2024. PMID: 39566612 Free article.
Strain regulation retards natural operation decay of perovskite solar cells.
Shen Y, Zhang T, Xu G, Steele JA, Chen X, Chen W, Zheng G, Li J, Guo B, Yang H, Wu Y, Lin X, Alshahrani T, Yin W, Zhu J, Wang F, Amassian A, Gao X, Zhang X, Gao F, Li Y, Li Y. Shen Y, et al. Among authors: steele ja. Nature. 2024 Nov;635(8040):882-889. doi: 10.1038/s41586-024-08161-x. Epub 2024 Oct 14. Nature. 2024. PMID: 39401517 Free PMC article.
167 results