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The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
Gruber A, Cornaciu I, Lass A, Schweiger M, Poeschl M, Eder C, Kumari M, Schoiswohl G, Wolinski H, Kohlwein SD, Zechner R, Zimmermann R, Oberer M. Gruber A, et al. Among authors: zechner r. J Biol Chem. 2010 Apr 16;285(16):12289-98. doi: 10.1074/jbc.M109.064469. Epub 2010 Feb 17. J Biol Chem. 2010. PMID: 20164531 Free PMC article.
The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively.
Cornaciu I, Boeszoermenyi A, Lindermuth H, Nagy HM, Cerk IK, Ebner C, Salzburger B, Gruber A, Schweiger M, Zechner R, Lass A, Zimmermann R, Oberer M. Cornaciu I, et al. Among authors: zechner r. PLoS One. 2011;6(10):e26349. doi: 10.1371/journal.pone.0026349. Epub 2011 Oct 19. PLoS One. 2011. PMID: 22039468 Free PMC article.
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R. Kumari M, et al. Among authors: zechner r. Cell Metab. 2012 May 2;15(5):691-702. doi: 10.1016/j.cmet.2012.04.008. Cell Metab. 2012. PMID: 22560221 Free PMC article.
G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase.
Schweiger M, Paar M, Eder C, Brandis J, Moser E, Gorkiewicz G, Grond S, Radner FP, Cerk I, Cornaciu I, Oberer M, Kersten S, Zechner R, Zimmermann R, Lass A. Schweiger M, et al. Among authors: zechner r. J Lipid Res. 2012 Nov;53(11):2307-17. doi: 10.1194/jlr.M027409. Epub 2012 Aug 13. J Lipid Res. 2012. PMID: 22891293 Free PMC article.
Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.
Nagy HM, Paar M, Heier C, Moustafa T, Hofer P, Haemmerle G, Lass A, Zechner R, Oberer M, Zimmermann R. Nagy HM, et al. Among authors: zechner r. Biochim Biophys Acta. 2014 Apr 4;1841(4):588-94. doi: 10.1016/j.bbalip.2014.01.005. Epub 2014 Jan 16. Biochim Biophys Acta. 2014. PMID: 24440819 Free PMC article.
249 results