Hougland JL - Search Results

1

Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization.

Pierce MR, Ji J, Novak SX, Sieburg MA, Nangia S, Nangia S, Hougland JL. Pierce MR, et al. Among authors: hougland jl. J Chem Inf Model. 2023 Nov 27;63(22):7159-7170. doi: 10.1021/acs.jcim.3c00917. Epub 2023 Nov 8. J Chem Inf Model. 2023. PMID: 37939203 Free PMC article.

2

Getting a handle on protein prenylation.

Hougland JL, Fierke CA. Hougland JL, et al. Nat Chem Biol. 2009 Apr;5(4):197-8. doi: 10.1038/nchembio0409-197. Nat Chem Biol. 2009. PMID: 19295521 No abstract available.

3

Using selective withdrawal to coat microparticles.

Cohen I, Li H, Hougland JL, Mrksich M, Nagel SR. Cohen I, et al. Among authors: hougland jl. Science. 2001 Apr 13;292(5515):265-7. doi: 10.1126/science.1059175. Science. 2001. PMID: 11303097

4

The 2'-hydroxyl group of the guanosine nucleophile donates a functionally important hydrogen bond in the tetrahymena ribozyme reaction.

Hougland JL, Sengupta RN, Dai Q, Deb SK, Piccirilli JA. Hougland JL, et al. Biochemistry. 2008 Jul 22;47(29):7684-94. doi: 10.1021/bi8000648. Epub 2008 Jun 24. Biochemistry. 2008. PMID: 18572927

5

Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice.

Wellman MK, Patterson ZR, MacKay H, Darling JE, Mani BK, Zigman JM, Hougland JL, Abizaid A. Wellman MK, et al. Among authors: hougland jl. Front Endocrinol (Lausanne). 2015 Sep 25;6:144. doi: 10.3389/fendo.2015.00144. eCollection 2015. Front Endocrinol (Lausanne). 2015. PMID: 26441834 Free PMC article.

6

A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase.

Darling JE, Prybolsky EP, Sieburg M, Hougland JL. Darling JE, et al. Among authors: hougland jl. Anal Biochem. 2013 Jun 1;437(1):68-76. doi: 10.1016/j.ab.2013.02.013. Epub 2013 Feb 27. Anal Biochem. 2013. PMID: 23453974

7

Ghrelin Octanoylation Is Completely Stabilized in Biological Samples by Alkyl Fluorophosphonates.

McGovern-Gooch KR, Rodrigues T, Darling JE, Sieburg MA, Abizaid A, Hougland JL. McGovern-Gooch KR, et al. Among authors: hougland jl. Endocrinology. 2016 Nov;157(11):4330-4338. doi: 10.1210/en.2016-1657. Epub 2016 Sep 13. Endocrinology. 2016. PMID: 27623288

8

Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.

McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, Chisholm JD, Hougland JL. McGovern-Gooch KR, et al. Among authors: hougland jl. Biochemistry. 2017 Feb 21;56(7):919-931. doi: 10.1021/acs.biochem.6b01008. Epub 2017 Feb 7. Biochemistry. 2017. PMID: 28134508 Free PMC article.

9

Biochemical Assays for Ghrelin Acylation and Inhibition of Ghrelin O-Acyltransferase.

Sieburg MA, Cleverdon ER, Hougland JL. Sieburg MA, et al. Among authors: hougland jl. Methods Mol Biol. 2019;2009:227-241. doi: 10.1007/978-1-4939-9532-5_18. Methods Mol Biol. 2019. PMID: 31152408

10

The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation.

Campaña MB, Irudayanathan FJ, Davis TR, McGovern-Gooch KR, Loftus R, Ashkar M, Escoffery N, Navarro M, Sieburg MA, Nangia S, Hougland JL. Campaña MB, et al. Among authors: hougland jl. J Biol Chem. 2019 Sep 27;294(39):14166-14174. doi: 10.1074/jbc.AC119.009749. Epub 2019 Aug 14. J Biol Chem. 2019. PMID: 31413115 Free PMC article.

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