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ERK1/2 Phosphorylation Predicts Survival in Recurrent Glioblastoma Following Intracerebral and Adjuvant PD-1/CTLA-4 Immunotherapy: A REMARK-guided Analysis.
Arrieta VA, Duerinck J, Burdett KB, Habashy KJ, Geens W, Gould A, Schwarze JK, Dmello C, Kim KS, Saganty R, Chen L, Moscona A, McCord M, Lee-Chang C, Horbinski CM, Zhang H, Stupp R, Neyns B, Sonabend AM. Arrieta VA, et al. Among authors: chen l. Clin Cancer Res. 2024 Jan 17;30(2):379-388. doi: 10.1158/1078-0432.CCR-23-1889. Clin Cancer Res. 2024. PMID: 37939133 Free PMC article.
ARF4-mediated retrograde trafficking as a driver of chemoresistance in glioblastoma.
Budhiraja S, McManus G, Baisiwala S, Perrault EN, Cho S, Saathoff M, Chen L, Park CH, Kazi HA, Dmello C, Lin P, James CD, Sonabend AM, Heiland DH, Ahmed AU. Budhiraja S, et al. Among authors: chen l. Neuro Oncol. 2024 Aug 5;26(8):1421-1437. doi: 10.1093/neuonc/noae059. Neuro Oncol. 2024. PMID: 38506351
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.
Kim KS, Habashy K, Gould A, Zhao J, Najem H, Amidei C, Saganty R, Arrieta VA, Dmello C, Chen L, Zhang DY, Castro B, Billingham L, Levey D, Huber O, Marques M, Savitsky DA, Morin BM, Muzzio M, Canney M, Horbinski C, Zhang P, Miska J, Padney S, Zhang B, Rabadan R, Phillips JJ, Butowski N, Heimberger AB, Hu J, Stupp R, Chand D, Lee-Chang C, Sonabend AM. Kim KS, et al. Among authors: chen l. Neuro Oncol. 2024 Nov 4;26(11):2044-2060. doi: 10.1093/neuonc/noae135. Neuro Oncol. 2024. PMID: 39028616
MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, microglia phenotype, and immune checkpoint blockade efficacy.
Kim KS, Zhang J, Arrieta VA, Dmello C, Grabis E, Habashy K, Duffy J, Zhao J, Gould A, Chen L, Hu J, Balyasnikova I, Chand D, Levey D, Canoll P, Zhao W, Sims PA, Rabadan R, Pandey S, Zhang B, Lee-Chang C, Heiland DH, Sonabend AM. Kim KS, et al. Among authors: chen l. bioRxiv [Preprint]. 2024 Sep 18:2024.09.11.612571. doi: 10.1101/2024.09.11.612571. bioRxiv. 2024. PMID: 39345374 Free PMC article. Preprint.
THOC1 complexes with SIN3A to regulate R-loops and promote glioblastoma progression.
Budhiraja S, Baisiwala S, Cho S, Chojak R, Kazi HA, Stepniak A, Perrault EN, Chen L, Park CH, Dmello C, Lin P, Sonabend AM, Ahmed AU. Budhiraja S, et al. Among authors: chen l. bioRxiv [Preprint]. 2024 Sep 26:2024.09.24.614748. doi: 10.1101/2024.09.24.614748. bioRxiv. 2024. PMID: 39386597 Free PMC article. Preprint.
Endothelial Response to Blood-Brain Barrier Disruption in the Human Brain.
Gould A, Luan Y, Hou Y, Korobova FV, Chen L, Arrieta VA, Amidei C, Ward R, Gomez C, Castro B, Habashy K, Zhang D, Youngblood M, Dmello C, Bebawy J, Bouchoux G, Stupp R, Canney M, Yue F, Iruela-Arispe ML, Sonabend AM. Gould A, et al. Among authors: chen l. JCI Insight. 2024 Dec 26:e187328. doi: 10.1172/jci.insight.187328. Online ahead of print. JCI Insight. 2024. PMID: 39724015 Free article.
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