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CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.
Zheng C, Wei Y, Zhang P, Lin K, He D, Teng H, Manyam G, Zhang Z, Liu W, Lee HRL, Tang X, He W, Islam N, Jain A, Chiu Y, Cao S, Diao Y, Meyer-Gauen S, Höök M, Malovannaya A, Li W, Hu M, Wang W, Xu H, Kopetz S, Chen Y. Zheng C, et al. Among authors: hu m. Nat Struct Mol Biol. 2023 Dec;30(12):1878-1892. doi: 10.1038/s41594-023-01117-1. Epub 2023 Nov 6. Nat Struct Mol Biol. 2023. PMID: 37932451 Free PMC article.
Circular ecDNA promotes accessible chromatin and high oncogene expression.
Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, Coruh C, Abnousi A, Houston J, Ye Z, Hu R, Yu M, Kim H, Law JA, Verhaak RGW, Hu M, Furnari FB, Chang HY, Ren B, Bafna V, Mischel PS. Wu S, et al. Among authors: hu m, hu r. Nature. 2019 Nov;575(7784):699-703. doi: 10.1038/s41586-019-1763-5. Epub 2019 Nov 20. Nature. 2019. PMID: 31748743 Free PMC article.
Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues.
Yu M, Zemke NR, Chen Z, Juric I, Hu R, Raviram R, Abnousi A, Fang R, Zhang Y, Gorkin DU, Li YE, Zhao Y, Lee L, Mishra S, Schmitt AD, Qiu Y, Dickel DE, Visel A, Pennacchio LA, Hu M, Ren B. Yu M, et al. Among authors: hu m, hu r. Nat Struct Mol Biol. 2024 Dec 16. doi: 10.1038/s41594-024-01431-2. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39681766
Cell-type-specific 3D epigenomes in the developing human cortex.
Song M, Pebworth MP, Yang X, Abnousi A, Fan C, Wen J, Rosen JD, Choudhary MNK, Cui X, Jones IR, Bergenholtz S, Eze UC, Juric I, Li B, Maliskova L, Lee J, Liu W, Pollen AA, Li Y, Wang T, Hu M, Kriegstein AR, Shen Y. Song M, et al. Among authors: hu m. Nature. 2020 Nov;587(7835):644-649. doi: 10.1038/s41586-020-2825-4. Epub 2020 Oct 14. Nature. 2020. PMID: 33057195 Free PMC article.
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation.
Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, Hocker JD, Conte M, Gorkin D, Yu M, Li B, Dixon JR, Hu M, Nicodemi M, Zhao H, Ren B. Kubo N, et al. Among authors: hu m, hu r. Nat Struct Mol Biol. 2021 Feb;28(2):152-161. doi: 10.1038/s41594-020-00539-5. Epub 2021 Jan 4. Nat Struct Mol Biol. 2021. PMID: 33398174 Free PMC article.
Genome-wide mapping and analysis of chromosome architecture.
Schmitt AD, Hu M, Ren B. Schmitt AD, et al. Among authors: hu m. Nat Rev Mol Cell Biol. 2016 Dec;17(12):743-755. doi: 10.1038/nrm.2016.104. Epub 2016 Sep 1. Nat Rev Mol Cell Biol. 2016. PMID: 27580841 Free PMC article. Review.
FIREcaller: Detecting frequently interacting regions from Hi-C data.
Crowley C, Yang Y, Qiu Y, Hu B, Abnousi A, Lipiński J, Plewczyński D, Wu D, Won H, Ren B, Hu M, Li Y. Crowley C, et al. Among authors: hu m, hu b. Comput Struct Biotechnol J. 2020 Dec 29;19:355-362. doi: 10.1016/j.csbj.2020.12.026. eCollection 2021. Comput Struct Biotechnol J. 2020. PMID: 33489005 Free PMC article.
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