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Targeting Complement C5a Receptor 1 for the Treatment of Immunosuppression in Sepsis.
Sommerfeld O, Medyukhina A, Neugebauer S, Ghait M, Ulferts S, Lupp A, König R, Wetzker R, Schulz S, Figge MT, Bauer M, Press AT. Sommerfeld O, et al. Among authors: neugebauer s. Mol Ther. 2021 Jan 6;29(1):338-346. doi: 10.1016/j.ymthe.2020.09.008. Epub 2020 Sep 5. Mol Ther. 2021. PMID: 32966769 Free PMC article.
Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk.
Leonhardt J, Dorresteijn MJ, Neugebauer S, Mihaylov D, Kunze J, Rubio I, Hohberger FS, Leonhardt S, Kiehntopf M, Stahl K, Bode C, David S, Wagener FADTG, Pickkers P, Bauer M. Leonhardt J, et al. Among authors: neugebauer s. Crit Care. 2023 Sep 27;27(1):372. doi: 10.1186/s13054-023-04620-5. Crit Care. 2023. PMID: 37759239 Free PMC article.
Lipid metabolic signatures deviate in sepsis survivors compared to non-survivors.
Khaliq W, Großmann P, Neugebauer S, Kleyman A, Domizi R, Calcinaro S, Brealey D, Gräler M, Kiehntopf M, Schäuble S, Singer M, Panagiotou G, Bauer M. Khaliq W, et al. Among authors: neugebauer s. Comput Struct Biotechnol J. 2020 Nov 21;18:3678-3691. doi: 10.1016/j.csbj.2020.11.009. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33304464 Free PMC article.
Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction.
Leonhardt J, Haider RS, Sponholz C, Leonhardt S, Drube J, Spengler K, Mihaylov D, Neugebauer S, Kiehntopf M, Lambert NA, Kortgen A, Bruns T, Tacke F, Hoffmann C, Bauer M, Heller R. Leonhardt J, et al. Among authors: neugebauer s. Cell Mol Gastroenterol Hepatol. 2021;12(1):25-40. doi: 10.1016/j.jcmgh.2021.01.011. Epub 2021 Feb 2. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33545429 Free PMC article.
Metabolic Profiling Identifies 1-MetHis and 3-IPA as Potential Diagnostic Biomarkers for Patients With Acute and Chronic Heart Failure With Reduced Ejection Fraction.
Kretzschmar T, Westphal J, Neugebauer S, Wu JMF, Zeller M, Bogoviku J, Bekhite MM, Bekfani T, Schlattmann P, Kiehntopf M, Franz M, Schulze PC. Kretzschmar T, et al. Among authors: neugebauer s. Circ Heart Fail. 2024 Jan;17(1):e010813. doi: 10.1161/CIRCHEARTFAILURE.123.010813. Epub 2024 Jan 5. Circ Heart Fail. 2024. PMID: 38179791 Free PMC article.
81 results