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Page 1
Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling.
Dudgeon C, Casabianca A, Harris C, Ogier C, Bellina M, Fiore S, Bernet A, Ducarouge B, Goldschneider D, Su X, Pitarresi J, Hezel A, De S, Narrow W, Soliman F, Shields C, Vendramini-Costa DB, Prela O, Wang L, Astsaturov I, Mehlen P, Carpizo DR. Dudgeon C, et al. Among authors: hezel a. Cell Rep. 2023 Nov 28;42(11):113369. doi: 10.1016/j.celrep.2023.113369. Epub 2023 Nov 3. Cell Rep. 2023. PMID: 37922311 Free article.
Neoadjuvant pemigatinib as a bridge to living donor liver transplantation for intrahepatic cholangiocarcinoma with FGFR2 gene rearrangement.
Byrne MM, Dunne RF, Melaragno JI, Chávez-Villa M, Hezel A, Liao X, Ertreo M, Al-Judaibi B, Orloff M, Hernandez-Alejandro R, Tomiyama K. Byrne MM, et al. Among authors: hezel a. Am J Transplant. 2024 Nov 6:S1600-6135(24)00683-X. doi: 10.1016/j.ajt.2024.10.023. Online ahead of print. Am J Transplant. 2024. PMID: 39515760
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression.
Asantewaa G, Tuttle ET, Ward NP, Kang YP, Kim Y, Kavanagh ME, Girnius N, Chen Y, Rodriguez K, Hecht F, Zocchi M, Smorodintsev-Schiller L, Scales TQ, Taylor K, Alimohammadi F, Duncan RP, Sechrist ZR, Agostini-Vulaj D, Schafer XL, Chang H, Smith ZR, O'Connor TN, Whelan S, Selfors LM, Crowdis J, Gray GK, Bronson RT, Brenner D, Rufini A, Dirksen RT, Hezel AF, Huber AR, Munger J, Cravatt BF, Vasiliou V, Cole CL, DeNicola GM, Harris IS. Asantewaa G, et al. Among authors: hezel af. Nat Commun. 2024 Jul 21;15(1):6152. doi: 10.1038/s41467-024-50454-2. Nat Commun. 2024. PMID: 39034312 Free PMC article.
Smad4 restricts injury-provoked biliary proliferation and carcinogenesis.
Alexander WB, Wang W, Hill MA, O'Dell MR, Ruffolo LI, Guo B, Jackson KM, Ullman N, Friedland SC, McCall MN, Patel A, Figueroa-Guilliani N, Georger M, Belt BA, Whitney-Miller CL, Linehan DC, Murphy PJ, Hezel AF. Alexander WB, et al. Among authors: hezel af. Dis Model Mech. 2024 Jun 1;17(6):dmm050358. doi: 10.1242/dmm.050358. Epub 2024 Feb 28. Dis Model Mech. 2024. PMID: 38415925 Free PMC article.
Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy: A Secondary Analysis of the OPRA Randomized Clinical Trial.
Thompson HM, Omer DM, Lin S, Kim JK, Yuval JB, Verheij FS, Qin LX, Gollub MJ, Wu AJ, Lee M, Patil S, Hezel AF, Marcet JE, Cataldo PA, Polite BN, Herzig DO, Liska D, Oommen S, Friel CM, Ternent CA, Coveler AL, Hunt SR, Garcia-Aguilar J; OPRA Consortium. Thompson HM, et al. Among authors: hezel af. JAMA Netw Open. 2024 Jan 2;7(1):e2350903. doi: 10.1001/jamanetworkopen.2023.50903. JAMA Netw Open. 2024. PMID: 38194231 Free PMC article. Clinical Trial.
Glutathione supports lipid abundance in vivo.
Asantewaa G, Tuttle ET, Ward NP, Kang YP, Kim Y, Kavanagh ME, Girnius N, Chen Y, Duncan R, Rodriguez K, Hecht F, Zocchi M, Smorodintsev-Schiller L, Scales TQ, Taylor K, Alimohammadi F, Sechrist ZR, Agostini-Vulaj D, Schafer XL, Chang H, Smith Z, O'Connor TN, Whelan S, Selfors LM, Crowdis J, Gray GK, Bronson RT, Brenner D, Rufini A, Dirksen RT, Hezel AF, Huber AR, Munger J, Cravatt BF, Vasiliou V, Cole CL, DeNicola GM, Harris IS. Asantewaa G, et al. Among authors: hezel af. bioRxiv [Preprint]. 2023 Feb 11:2023.02.10.524960. doi: 10.1101/2023.02.10.524960. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 21;15(1):6152. doi: 10.1038/s41467-024-50454-2 PMID: 36798186 Free PMC article. Updated. Preprint.
Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Williams HL, Dias Costa A, Zhang J, Raghavan S, Winter PS, Kapner KS, Ginebaugh SP, Väyrynen SA, Väyrynen JP, Yuan C, Navia AW, Wang J, Yang A, Bosse TL, Kalekar RL, Lowder KE, Lau MC, Elganainy D, Morales-Oyarvide V, Rubinson DA, Singh H, Perez K, Cleary JM, Clancy TE, Wang J, Mancias JD, Brais LK, Hill ER, Kozak MM, Linehan DC, Dunne RF, Chang DT, Koong AC, Hezel AF, Hahn WC, Shalek AK, Aguirre AJ, Nowak JA, Wolpin BM. Williams HL, et al. Among authors: hezel af. Cancer Res. 2023 Feb 3;83(3):441-455. doi: 10.1158/0008-5472.CAN-22-3050. Cancer Res. 2023. PMID: 36459568 Free PMC article.
83 results