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Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis.
Bella Á, Arrizabalaga L, Di Trani CA, Gonzalez-Gomariz J, Gomar C, Russo-Cabrera JS, Olivera I, Cirella A, Fernandez-Sendin M, Alvarez M, Teijeira A, Atay C, Medina-Echeverz J, Hinterberger M, Hochrein H, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: berraondo p. J Immunother Cancer. 2023 Nov;11(11):e006702. doi: 10.1136/jitc-2023-006702. J Immunother Cancer. 2023. PMID: 37918917 Free PMC article.
Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.
Tirapu I, Huarte E, Guiducci C, Arina A, Zaratiegui M, Murillo O, Gonzalez A, Berasain C, Berraondo P, Fortes P, Prieto J, Colombo MP, Chen L, Melero I. Tirapu I, et al. Among authors: berraondo p. Cancer Res. 2006 Feb 15;66(4):2442-50. doi: 10.1158/0008-5472.CAN-05-1681. Cancer Res. 2006. PMID: 16489051 Free article.
In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.
Murillo O, Dubrot J, Palazón A, Arina A, Azpilikueta A, Alfaro C, Solano S, Ochoa MC, Berasain C, Gabari I, Pérez-Gracia JL, Berraondo P, Hervás-Stubbs S, Melero I. Murillo O, et al. Among authors: berraondo p. Eur J Immunol. 2009 Sep;39(9):2424-36. doi: 10.1002/eji.200838958. Eur J Immunol. 2009. PMID: 19662633 Free article.
Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.
Gonzalez-Aparicio M, Alzuguren P, Mauleon I, Medina-Echeverz J, Hervas-Stubbs S, Mancheno U, Berraondo P, Crettaz J, Gonzalez-Aseguinolaza G, Prieto J, Hernandez-Alcoceba R. Gonzalez-Aparicio M, et al. Among authors: berraondo p. Gut. 2011 Mar;60(3):341-9. doi: 10.1136/gut.2010.211722. Epub 2010 Sep 20. Gut. 2011. PMID: 20855451 Free article.
172 results