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Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis.
Bahudhanapati H, Tan J, Apel RM, Seeliger B, Schupp J, Li X, Sullivan DI, Sembrat J, Rojas M, Tabib T, Valenzi E, Lafyatis R, Mitash N, Hernandez Pineda R, Jawale C, Peroumal D, Biswas P, Tedrow J, Adams T, Kaminski N, Wuyts WA, McDyer JF, Gibson KF, Alder JK, Königshoff M, Zhang Y, Nouraie M, Prasse A, Kass DJ. Bahudhanapati H, et al. Among authors: sembrat j. Eur Respir J. 2024 Jan 4;63(1):2300088. doi: 10.1183/13993003.00088-2023. Print 2024 Jan. Eur Respir J. 2024. PMID: 37918852
Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis.
Morse C, Tabib T, Sembrat J, Buschur KL, Bittar HT, Valenzi E, Jiang Y, Kass DJ, Gibson K, Chen W, Mora A, Benos PV, Rojas M, Lafyatis R. Morse C, et al. Among authors: sembrat j. Eur Respir J. 2019 Aug 22;54(2):1802441. doi: 10.1183/13993003.02441-2018. Print 2019 Aug. Eur Respir J. 2019. PMID: 31221805 Free PMC article.
Single-nucleus chromatin accessibility identifies a critical role for TWIST1 in idiopathic pulmonary fibrosis myofibroblast activity.
Valenzi E, Bahudhanapati H, Tan J, Tabib T, Sullivan DI, Nouraie M, Sembrat J, Fan L, Chen K, Liu S, Rojas M, Lafargue A, Felsher DW, Tran PT, Kass DJ, Lafyatis R. Valenzi E, et al. Among authors: sembrat j. Eur Respir J. 2023 Jul 7;62(1):2200474. doi: 10.1183/13993003.00474-2022. Print 2023 Jul. Eur Respir J. 2023. PMID: 37142338 Free PMC article.
VCAM-1 is a TGF-β1 inducible gene upregulated in idiopathic pulmonary fibrosis.
Agassandian M, Tedrow JR, Sembrat J, Kass DJ, Zhang Y, Goncharova EA, Kaminski N, Mallampalli RK, Vuga LJ. Agassandian M, et al. Among authors: sembrat j. Cell Signal. 2015 Dec;27(12):2467-73. doi: 10.1016/j.cellsig.2015.09.003. Epub 2015 Sep 18. Cell Signal. 2015. PMID: 26386411 Free PMC article.
MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis.
Bahudhanapati H, Tan J, Dutta JA, Strock SB, Sembrat J, Àlvarez D, Rojas M, Jäger B, Prasse A, Zhang Y, Kass DJ. Bahudhanapati H, et al. Among authors: sembrat j. J Biol Chem. 2019 Mar 29;294(13):5008-5022. doi: 10.1074/jbc.RA118.004910. Epub 2019 Feb 1. J Biol Chem. 2019. PMID: 30709904 Free PMC article.
GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis.
Zhang Y, Jiang M, Nouraie M, Roth MG, Tabib T, Winters S, Chen X, Sembrat J, Chu Y, Cardenes N, Tuder RM, Herzog EL, Ryu C, Rojas M, Lafyatis R, Gibson KF, McDyer JF, Kass DJ, Alder JK. Zhang Y, et al. Among authors: sembrat j. Am J Physiol Lung Cell Mol Physiol. 2019 Oct 1;317(4):L510-L521. doi: 10.1152/ajplung.00062.2019. Epub 2019 Aug 21. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31432710 Free PMC article.
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