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Page 1
Liver type 1 innate lymphoid cells undergo apoptosis in murine models of macrophage activation syndrome and are dispensable for disease.
De Visscher A, Vandeput M, Vandenhaute J, Malengier-Devlies B, Bernaerts E, Ahmadzadeh K, Filtjens J, Mitera T, Berghmans N, Van den Steen PE, Friedrich C, Gasteiger G, Wouters C, Matthys P. De Visscher A, et al. Among authors: gasteiger g. Eur J Immunol. 2024 Dec;54(12):e2451043. doi: 10.1002/eji.202451043. Epub 2024 Sep 30. Eur J Immunol. 2024. PMID: 39348088
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2.
Vogt M, Dudvarski Stankovic N, Cruz Garcia Y, Hofstetter J, Schneider K, Kuybu F, Hauck T, Adhikari B, Hamann A, Rocca Y, Grysczyk L, Martin B, Gebhardt-Wolf A, Wiegering A, Diefenbacher M, Gasteiger G, Knapp S, Saur D, Eilers M, Rosenfeldt M, Erhard F, Vos SM, Wolf E. Vogt M, et al. Among authors: gasteiger g. Gut. 2024 Aug 8;73(9):1509-1528. doi: 10.1136/gutjnl-2023-331519. Gut. 2024. PMID: 38821858 Free PMC article.
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming.
Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M. Wu H, et al. Among authors: gasteiger g. Nat Commun. 2023 Oct 27;14(1):6858. doi: 10.1038/s41467-023-42634-3. Nat Commun. 2023. PMID: 37891230 Free PMC article.
Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks.
Ugur M, Labios RJ, Fenton C, Knöpper K, Jobin K, Imdahl F, Golda G, Hoh K, Grafen A, Kaisho T, Saliba AE, Grün D, Gasteiger G, Bajénoff M, Kastenmüller W. Ugur M, et al. Among authors: gasteiger g. Immunity. 2023 Aug 8;56(8):1778-1793.e10. doi: 10.1016/j.immuni.2023.06.020. Epub 2023 Jul 17. Immunity. 2023. PMID: 37463581 Free PMC article.
ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery.
Jakob MO, Spari D, Sànchez Taltavull D, Salm L, Yilmaz B, Doucet Ladevèze R, Mooser C, Pereyra D, Ouyang Y, Schmidt T, Mattiola I, Starlinger P, Stroka D, Tschan F, Candinas D, Gasteiger G, Klose CSN, Diefenbach A, Gomez de Agüero M, Beldi G. Jakob MO, et al. Among authors: gasteiger g. Cell Rep. 2023 Mar 28;42(3):112269. doi: 10.1016/j.celrep.2023.112269. Epub 2023 Mar 17. Cell Rep. 2023. PMID: 36933213 Free PMC article.
Hepatitis B Virus Targets Lipid Transport Pathways to Infect Hepatocytes.
Esser K, Cheng X, Wettengel JM, Lucifora J, Hansen-Palmus L, Austen K, Roca Suarez AA, Heintz S, Testoni B, Nebioglu F, Pham MT, Yang S, Zernecke A, Wohlleber D, Ringelhan M, Broxtermann M, Hartmann D, Hüser N, Mergner J, Pichlmair A, Thasler WE, Heikenwalder M, Gasteiger G, Blutke A, Walch A, Knolle PA, Bartenschlager R, Protzer U. Esser K, et al. Among authors: gasteiger g. Cell Mol Gastroenterol Hepatol. 2023;16(2):201-221. doi: 10.1016/j.jcmgh.2023.03.011. Epub 2023 Apr 11. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37054914 Free PMC article.
Autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells.
Sparano C, Solís-Sayago D, Zangger NS, Rindlisbacher L, Van Hove H, Vermeer M, Westermann F, Mussak C, Rallo E, Dergun S, Litscher G, Xu Y, Bijnen M, Friedrich C, Greter M, Juranić Lisnić V, Becher B, Gasteiger G, Oxenius A, Tugues S. Sparano C, et al. Among authors: gasteiger g. J Exp Med. 2025 Mar 3;222(3):e20240930. doi: 10.1084/jem.20240930. Epub 2024 Dec 18. J Exp Med. 2025. PMID: 39692745
PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma.
Gaballa A, Gebhardt-Wolf A, Krenz B, Mattavelli G, John M, Cossa G, Andreani S, Schülein-Völk C, Montesinos F, Vidal R, Kastner C, Ade CP, Kneitz B, Gasteiger G, Gallant P, Rosenfeldt M, Riedel A, Eilers M. Gaballa A, et al. Among authors: gasteiger g. Nat Commun. 2024 Feb 16;15(1):1446. doi: 10.1038/s41467-024-45760-8. Nat Commun. 2024. PMID: 38365788 Free PMC article.
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection.
Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G. Torcellan T, et al. Among authors: gasteiger g. Immunity. 2024 Jan 9;57(1):124-140.e7. doi: 10.1016/j.immuni.2023.11.018. Epub 2023 Dec 28. Immunity. 2024. PMID: 38157853 Free PMC article.
66 results