Christofk HR - Search Results

1

Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma.

Galvan C, Flores A, Cerrillos V, Avila I, Murphy C, Zheng W, To TT, Christofk HR, Lowry WE. Galvan C, et al. Among authors: christofk hr. bioRxiv [Preprint]. 2023 Oct 19:2023.10.16.562128. doi: 10.1101/2023.10.16.562128. bioRxiv. 2023. Update in: Sci Adv. 2024 Sep 20;10(38):eadn2806. doi: 10.1126/sciadv.adn2806 PMID: 37905122 Free PMC article. Updated. Preprint.

2

TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.

Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. Watanabe M, et al. Among authors: christofk hr. Stem Cell Reports. 2022 Oct 11;17(10):2220-2238. doi: 10.1016/j.stemcr.2022.08.013. Epub 2022 Sep 29. Stem Cell Reports. 2022. PMID: 36179695 Free PMC article.

3

Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma.

Flinders C, Lam L, Rubbi L, Ferrari R, Fitz-Gibbon S, Chen PY, Thompson M, Christofk H, B Agus D, Ruderman D, Mallick P, Pellegrini M. Flinders C, et al. Genome Med. 2016 May 4;8(1):54. doi: 10.1186/s13073-016-0305-0. Genome Med. 2016. PMID: 27146673 Free PMC article.

4

Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment.

Braas D, Ahler E, Tam B, Nathanson D, Riedinger M, Benz MR, Smith KB, Eilber FC, Witte ON, Tap WD, Wu H, Christofk HR. Braas D, et al. Among authors: christofk hr. Cancer Discov. 2012 Dec;2(12):1109-17. doi: 10.1158/2159-8290.CD-12-0197. Cancer Discov. 2012. PMID: 23230188 Free PMC article.

5

MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.

Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR. Hong CS, et al. Among authors: christofk hr. Cell Rep. 2016 Feb 23;14(7):1590-1601. doi: 10.1016/j.celrep.2016.01.057. Epub 2016 Feb 11. Cell Rep. 2016. PMID: 26876179 Free PMC article.

6

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ, Amador-Noguez D, Christofk HR, Wagner G, Rabinowitz JD, Asara JM, Cantley LC. Vander Heiden MG, et al. Among authors: christofk hr. Science. 2010 Sep 17;329(5998):1492-9. doi: 10.1126/science.1188015. Science. 2010. PMID: 20847263 Free PMC article.

7

FH Variant Pathogenicity Promotes Purine Salvage Pathway Dependence in Kidney Cancer.

Wilde BR, Chakraborty N, Matulionis N, Hernandez S, Ueno D, Gee ME, Esplin ED, Ouyang K, Nykamp K, Shuch B, Christofk HR. Wilde BR, et al. Among authors: christofk hr. Cancer Discov. 2023 Sep 6;13(9):2072-2089. doi: 10.1158/2159-8290.CD-22-0874. Cancer Discov. 2023. PMID: 37255402 Free PMC article.

8

Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy.

Sperry J, Condro MC, Guo L, Braas D, Vanderveer-Harris N, Kim KKO, Pope WB, Divakaruni AS, Lai A, Christofk H, Castro MG, Lowenstein PR, Le Belle JE, Kornblum HI. Sperry J, et al. iScience. 2020 Aug 13;23(9):101453. doi: 10.1016/j.isci.2020.101453. eCollection 2020 Sep 25. iScience. 2020. PMID: 32861192 Free PMC article.

9

Rethinking glutamine addiction.

Krall AS, Christofk HR. Krall AS, et al. Among authors: christofk hr. Nat Cell Biol. 2015 Dec;17(12):1515-7. doi: 10.1038/ncb3278. Nat Cell Biol. 2015. PMID: 26612572

10

Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome.

Zhang S, Williams KJ, Verlande-Ferrero A, Chan AP, Su GB, Kershaw EE, Cox JE, Maschek JA, Shapira SN, Christofk HR, de Aguiar Vallim TQ, Masri S, Villanueva CJ. Zhang S, et al. Among authors: christofk hr. J Lipid Res. 2024 Feb;65(2):100434. doi: 10.1016/j.jlr.2023.100434. Epub 2023 Aug 26. J Lipid Res. 2024. PMID: 37640283 Free PMC article.

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