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255 results

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Page 1
Effects of the maternal and fetal proteome on birth weight: a Mendelian randomization analysis.
McBride N, Fernández-Sanlés A, Arab MA, Bond TA, Zheng J, Magnus MC, Corfield EC, Clayton GL, Hwang LD, Beaumont RN, Evans DM, Freathy RM, Gaunt TR, Lawlor DA, Borges MC. McBride N, et al. Among authors: gaunt tr. medRxiv [Preprint]. 2023 Oct 21:2023.10.20.23297135. doi: 10.1101/2023.10.20.23297135. medRxiv. 2023. PMID: 37904919 Free PMC article. Preprint.
Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis.
Borges MC, Barros AJD, Ferreira DLS, Casas JP, Horta BL, Kivimaki M, Kumari M, Menon U, Gaunt TR, Ben-Shlomo Y, Freitas DF, Oliveira IO, Gentry-Maharaj A, Fourkala E, Lawlor DA, Hingorani AD. Borges MC, et al. Among authors: gaunt tr. Circ Cardiovasc Genet. 2017 Dec;10(6):e001837. doi: 10.1161/CIRCGENETICS.117.001837. Circ Cardiovasc Genet. 2017. PMID: 29237687 Free PMC article.
Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study.
De Silva NMG, Borges MC, Hingorani AD, Engmann J, Shah T, Zhang X, Luan J, Langenberg C, Wong A, Kuh D, Chambers JC, Zhang W, Jarvelin MR, Sebert S, Auvinen J; UCLEB consortium; Gaunt TR, Lawlor DA. De Silva NMG, et al. Among authors: gaunt tr. Diabetes. 2019 Aug;68(8):1681-1691. doi: 10.2337/db18-1048. Epub 2019 May 14. Diabetes. 2019. PMID: 31088856 Free PMC article.
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR. Zheng J, et al. Among authors: gaunt tr. Int J Epidemiol. 2022 Jan 6;50(6):1995-2010. doi: 10.1093/ije/dyab203. Epub 2021 Oct 20. Int J Epidemiol. 2022. PMID: 34999880 Free PMC article.
The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.
Borges MC, Haycock P, Zheng J, Hemani G, Howe LJ, Schmidt AF, Staley JR, Lumbers RT, Henry A, Lemaitre RN, Gaunt TR, Holmes MV, Davey Smith G, Hingorani AD, Lawlor DA. Borges MC, et al. Among authors: gaunt tr. Hum Mol Genet. 2022 Nov 28;31(23):4034-4054. doi: 10.1093/hmg/ddac153. Hum Mol Genet. 2022. PMID: 35796550 Free PMC article.
Design and quality control of large-scale two-sample Mendelian randomization studies.
Haycock PC, Borges MC, Burrows K, Lemaitre RN, Harrison S, Burgess S, Chang X, Westra J, Khankari NK, Tsilidis KK, Gaunt T, Hemani G, Zheng J, Truong T, O'Mara TA, Spurdle AB, Law MH, Slager SL, Birmann BM, Saberi Hosnijeh F, Mariosa D, Amos CI, Hung RJ, Zheng W, Gunter MJ, Davey Smith G, Relton C, Martin RM; Fatty Acids in Cancer Mendelian Randomization Collaboration. Haycock PC, et al. Int J Epidemiol. 2023 Apr 12;52(5):1498-1521. doi: 10.1093/ije/dyad018. eCollection 2023 Oct. Int J Epidemiol. 2023. PMID: 38587501 Free PMC article.
Transcriptome-wide Mendelian randomization during CD4+ T cell activation reveals immune-related drug targets for cardiometabolic diseases.
Wu X, Ying H, Yang Q, Yang Q, Liu H, Ding Y, Zhao H, Chen Z, Zheng R, Lin H, Wang S, Li M, Wang T, Zhao Z, Xu M, Chen Y, Xu Y, Vincent EE, Borges MC, Gaunt TR, Ning G, Wang W, Bi Y, Zheng J, Lu J. Wu X, et al. Among authors: gaunt tr. Nat Commun. 2024 Oct 28;15(1):9302. doi: 10.1038/s41467-024-53621-7. Nat Commun. 2024. PMID: 39468075 Free PMC article.
Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.
De Silva NM, Freathy RM, Palmer TM, Donnelly LA, Luan J, Gaunt T, Langenberg C, Weedon MN, Shields B, Knight BA, Ward KJ, Sandhu MS, Harbord RM, McCarthy MI, Smith GD, Ebrahim S, Hattersley AT, Wareham N, Lawlor DA, Morris AD, Palmer CN, Frayling TM. De Silva NM, et al. Diabetes. 2011 Mar;60(3):1008-18. doi: 10.2337/db10-1317. Epub 2011 Jan 31. Diabetes. 2011. PMID: 21282362 Free PMC article.
255 results