Broca C - Search Results

1

GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function.

Zaïmia N, Obeid J, Varrault A, Sabatier J, Broca C, Gilon P, Costes S, Bertrand G, Ravier MA. Zaïmia N, et al. Among authors: broca c. Cell Rep. 2023 Nov 28;42(11):113326. doi: 10.1016/j.celrep.2023.113326. Epub 2023 Oct 31. Cell Rep. 2023. PMID: 37897727 Free article.

2

beta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells.

Broca C, Quoyer J, Costes S, Linck N, Varrault A, Deffayet PM, Bockaert J, Dalle S, Bertrand G. Broca C, et al. J Biol Chem. 2009 Feb 13;284(7):4332-42. doi: 10.1074/jbc.M807595200. Epub 2008 Dec 11. J Biol Chem. 2009. PMID: 19074139 Free article.

3

Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment.

Ruiz L, Gurlo T, Ravier MA, Wojtusciszyn A, Mathieu J, Brown MR, Broca C, Bertrand G, Butler PC, Matveyenko AV, Dalle S, Costes S. Ruiz L, et al. Among authors: broca c. Cell Death Dis. 2018 May 22;9(6):600. doi: 10.1038/s41419-018-0603-0. Cell Death Dis. 2018. PMID: 29789539 Free PMC article.

4

The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions.

Brown MR, Laouteouet D, Delobel M, Villard O, Broca C, Bertrand G, Wojtusciszyn A, Dalle S, Ravier MA, Matveyenko AV, Costes S. Brown MR, et al. Among authors: broca c. Cell Death Dis. 2022 Apr 15;13(4):353. doi: 10.1038/s41419-022-04767-z. Cell Death Dis. 2022. PMID: 35428762 Free PMC article.

5

GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells.

Quoyer J, Longuet C, Broca C, Linck N, Costes S, Varin E, Bockaert J, Bertrand G, Dalle S. Quoyer J, et al. Among authors: broca c. J Biol Chem. 2010 Jan 15;285(3):1989-2002. doi: 10.1074/jbc.M109.067207. Epub 2009 Nov 13. J Biol Chem. 2010. PMID: 19915011 Free PMC article.

6

Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.

Varin EM, Wojtusciszyn A, Broca C, Muller D, Ravier MA, Ceppo F, Renard E, Tanti JF, Dalle S. Varin EM, et al. Among authors: broca c. Cell Death Dis. 2016 Jan 21;7(1):e2065. doi: 10.1038/cddis.2015.399. Cell Death Dis. 2016. PMID: 26794660 Free PMC article.

7

ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival.

Costes S, Broca C, Bertrand G, Lajoix AD, Bataille D, Bockaert J, Dalle S. Costes S, et al. Among authors: broca c. Diabetes. 2006 Aug;55(8):2220-30. doi: 10.2337/db05-1618. Diabetes. 2006. PMID: 16873684

8

Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets.

Costes S, Vandewalle B, Tourrel-Cuzin C, Broca C, Linck N, Bertrand G, Kerr-Conte J, Portha B, Pattou F, Bockaert J, Dalle S. Costes S, et al. Among authors: broca c. Diabetes. 2009 May;58(5):1105-15. doi: 10.2337/db08-0926. Epub 2009 Feb 17. Diabetes. 2009. PMID: 19223597 Free PMC article.

9

Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.

Tariq M, de Souza AH, Bensellam M, Chae H, Jaffredo M, Close AF, Deglasse JP, Santos LRB, Buemi A, Mourad NI, Wojtusciszyn A, Raoux M, Gilon P, Broca C, Jonas JC. Tariq M, et al. Among authors: broca c. Diabetologia. 2023 Apr;66(4):709-723. doi: 10.1007/s00125-022-05842-y. Epub 2022 Dec 2. Diabetologia. 2023. PMID: 36459178

10

Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans.

Dalle S, Longuet C, Costes S, Broca C, Faruque O, Fontés G, Hani EH, Bataille D. Dalle S, et al. Among authors: broca c. J Biol Chem. 2004 May 7;279(19):20345-55. doi: 10.1074/jbc.M312483200. Epub 2004 Feb 26. J Biol Chem. 2004. PMID: 14988413 Free article.

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