Shi YL - Search Results

1

Design, synthesis and triglyceride-lowering activity of tricyclic matrine derivatives for the intervention of non-alcoholic fatty liver disease.

Zhu JY, Tang M, Li H, Shi YL, Li YM, Li YH, Ma XC, Duan QL, Mei YH, He HW, Zhang N, Peng ZG, Song DQ. Zhu JY, et al. Among authors: shi yl. Bioorg Chem. 2024 Jan;142:106925. doi: 10.1016/j.bioorg.2023.106925. Epub 2023 Oct 18. Bioorg Chem. 2024. PMID: 37890213 Review.

2

Structure-activity relationship and biological evaluation of 12 N-substituted aloperine derivatives as PD-L1 down-regulatory agents through proteasome pathway.

Zeng QX, Wang K, Zhang X, Shi YL, Dou YY, Guo ZH, Zhang XT, Zhang N, Deng HB, Li YH, Song DQ. Zeng QX, et al. Among authors: shi yl. Bioorg Chem. 2021 Dec;117:105432. doi: 10.1016/j.bioorg.2021.105432. Epub 2021 Oct 16. Bioorg Chem. 2021. PMID: 34678602

3

Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism.

Zhang X, Shi Y, Guo Z, Zhao X, Wu J, Cao S, Liu Y, Li Y, Huang W, Wang Y, Liu Q, Li Y, Song D. Zhang X, et al. Eur J Med Chem. 2022 Apr 15;234:114209. doi: 10.1016/j.ejmech.2022.114209. Epub 2022 Mar 5. Eur J Med Chem. 2022. PMID: 35279610 Free PMC article.

4

Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3-Kinase/Akt Phosphorylation.

Fan T, Cheng Y, Wei W, Zeng Q, Guo X, Guo Z, Li Y, Zhao L, Shi Y, Zhang X, Jiang J, Wang Y, Kong W, Song D. Fan T, et al. J Med Chem. 2022 May 26;65(10):7399-7413. doi: 10.1021/acs.jmedchem.2c00592. Epub 2022 May 13. J Med Chem. 2022. PMID: 35549263

5

Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects.

Wei W, Zeng Q, Wang Y, Guo X, Fan T, Li Y, Deng H, Zhao L, Zhang X, Liu Y, Shi Y, Zhu J, Ma X, Wang Y, Jiang J, Song D. Wei W, et al. Acta Pharm Sin B. 2023 May;13(5):2138-2151. doi: 10.1016/j.apsb.2022.12.009. Epub 2022 Dec 14. Acta Pharm Sin B. 2023. PMID: 37250154 Free PMC article.

6

Evolution and Discovery of Matrine Derivatives as a New Class of Anti-Hepatic Fibrosis Agents Targeting Ewing Sarcoma Breakpoint Region 1 (EWSR1).

Bao Y, Niu T, Zhu J, Mei Y, Shi Y, Meng R, Duan Q, Zhang N, Fan T, Wang Y, Pang Y, Li Y, He H, Song D. Bao Y, et al. J Med Chem. 2023 Jun 22;66(12):7969-7987. doi: 10.1021/acs.jmedchem.3c00286. Epub 2023 Jun 9. J Med Chem. 2023. PMID: 37294950

7

Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo.

Dong S, Hu K, Shi Y, Wang G, Yu D, Zhao Y, Zhang H, Wang Y, Sun H, Xu Z, Jia Q, Li Y, Li Y, Li B, Shi J, Zhu W. Dong S, et al. Bioorg Med Chem Lett. 2024 Jan 15;98:129590. doi: 10.1016/j.bmcl.2023.129590. Epub 2023 Dec 12. Bioorg Med Chem Lett. 2024. PMID: 38092072

8

Erratum: Author correction to 'Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects' [Acta Pharmaceutica Sinica B 13 (2023) 2138-2151].

Wei W, Zeng Q, Wang Y, Guo X, Fan T, Li Y, Deng H, Zhao L, Zhang X, Liu Y, Shi Y, Zhu J, Ma X, Wang Y, Jiang J, Song D. Wei W, et al. Acta Pharm Sin B. 2024 Mar;14(3):1477. doi: 10.1016/j.apsb.2023.12.014. Epub 2023 Dec 29. Acta Pharm Sin B. 2024. PMID: 38486984 Free PMC article.

9

Discovery and development of novel 10,12-disubstituted aloperine derivatives against HCoV-OC43 by targeting allosteric site of host TMPRSS2.

Meng R, Zhong X, Gong Y, Shi Y, Li J, Wu Z, Duan Q, Zhang X, Mei Y, Zhu J, Peng Z, Li Y, Song D. Meng R, et al. Bioorg Chem. 2024 Jun;147:107317. doi: 10.1016/j.bioorg.2024.107317. Epub 2024 Mar 27. Bioorg Chem. 2024. PMID: 38583252

10

One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups.

Dong S, Zhao Y, Shi Y, Xu Z, Shen J, Jia Q, Li Y, Chen K, Li B, Zhu W. Dong S, et al. Org Biomol Chem. 2021 Feb 25;19(7):1580-1588. doi: 10.1039/d0ob02477e. Org Biomol Chem. 2021. PMID: 33522535

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