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Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia.
Ehrmann S, Barbier F, Demiselle J, Quenot JP, Herbrecht JE, Roux D, Lacherade JC, Landais M, Seguin P, Schnell D, Veinstein A, Gouin P, Lasocki S, Lu Q, Beduneau G, Ferrandiere M, Plantefève G, Dahyot-Fizelier C, Chebib N, Mercier E, Heuzé-Vourc'h N, Respaud R, Gregoire N, Garot D, Nay MA, Meziani F, Andreu P, Clere-Jehl R, Zucman N, Azaïs MA, Saint-Martin M, Gandonnière CS, Benzekri D, Merdji H, Tavernier E; Reva and CRICS-TRIGGERSEP F-CRIN Research Networks. Ehrmann S, et al. Among authors: gregoire n. N Engl J Med. 2023 Nov 30;389(22):2052-2062. doi: 10.1056/NEJMoa2310307. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888914 Clinical Trial.
Pharmacokinetic/pharmacodynamic analysis of ceftazidime/avibactam and fosfomycin combinations in an in vitro hollow fiber infection model against multidrug-resistant Escherichia coli.
Kroemer N, Amann LF, Farooq A, Pfaffendorf C, Martens M, Decousser J-W, Grégoire N, Nordmann P, Wicha SG. Kroemer N, et al. Among authors: gregoire n. Microbiol Spectr. 2024 Jan 11;12(1):e0331823. doi: 10.1128/spectrum.03318-23. Epub 2023 Dec 8. Microbiol Spectr. 2024. PMID: 38063387 Free PMC article.
Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling.
Deroche L, Aranzana-Climent V, Rozenholc A, Prouvensier L, Darnaud L, Grégoire N, Marchand S, Ploy M-C, François B, Couet W, Barraud O, Buyck JM. Deroche L, et al. Among authors: gregoire n. Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0048023. doi: 10.1128/aac.00480-23. Epub 2023 Sep 11. Antimicrob Agents Chemother. 2023. PMID: 37695298 Free PMC article.
An improved PKPD modeling approach to characterize the pharmacodynamic interaction over time between ceftazidime/avibactam and colistin from in vitro time-kill experiments against multidrug-resistant Klebsiella pneumoniae isolates.
Aubry R, Buyck J, Prouvensier L, Decousser J-W, Nordmann P, Wicha SG, Marchand S, Grégoire N. Aubry R, et al. Among authors: gregoire n. Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0030123. doi: 10.1128/aac.00301-23. Epub 2023 Sep 8. Antimicrob Agents Chemother. 2023. PMID: 37681977 Free PMC article.
119 results