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Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS. Cerosaletti K, et al. J Immunol. 2017 Jul 1;199(1):323-335. doi: 10.4049/jimmunol.1700172. Epub 2017 May 31. J Immunol. 2017. PMID: 28566371 Free PMC article.
A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders.
Wambre E, Bajzik V, DeLong JH, O'Brien K, Nguyen QA, Speake C, Gersuk VH, DeBerg HA, Whalen E, Ni C, Farrington M, Jeong D, Robinson D, Linsley PS, Vickery BP, Kwok WW. Wambre E, et al. Among authors: linsley ps. Sci Transl Med. 2017 Aug 2;9(401):eaam9171. doi: 10.1126/scitranslmed.aam9171. Sci Transl Med. 2017. PMID: 28768806 Free PMC article. Clinical Trial.
A composite immune signature parallels disease progression across T1D subjects.
Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James EA, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA. Speake C, et al. JCI Insight. 2019 Dec 5;4(23):e126917. doi: 10.1172/jci.insight.126917. JCI Insight. 2019. PMID: 31671072 Free PMC article.
332 results