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SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, Wallace T, Dunn C, Nguyen C, Chia CW, Fan J, Ruffolo J, Zukley L, Shi G, Amano T, An Y, Meirelles O, Wu WW, Chou CK, Shen RF, Willis RA, Ko MSH, Liu YT, De S, Pierce BG, Ferrucci L, Egan J, Mariuzza R, Weng NP. Choy C, et al. Among authors: de s. Nat Commun. 2023 Oct 23;14(1):6725. doi: 10.1038/s41467-023-42430-z. Nat Commun. 2023. PMID: 37872153 Free PMC article.
Extracellular RNA profiles with human age.
Dluzen DF, Noren Hooten N, De S, Wood WH 3rd, Zhang Y, Becker KG, Zonderman AB, Tanaka T, Ferrucci L, Evans MK. Dluzen DF, et al. Among authors: de s. Aging Cell. 2018 Aug;17(4):e12785. doi: 10.1111/acel.12785. Epub 2018 May 24. Aging Cell. 2018. PMID: 29797538 Free PMC article.
Skeletal muscle transcriptome in healthy aging.
Tumasian RA 3rd, Harish A, Kundu G, Yang JH, Ubaida-Mohien C, Gonzalez-Freire M, Kaileh M, Zukley LM, Chia CW, Lyashkov A, Wood WH 3rd, Piao Y, Coletta C, Ding J, Gorospe M, Sen R, De S, Ferrucci L. Tumasian RA 3rd, et al. Among authors: de s. Nat Commun. 2021 Apr 1;12(1):2014. doi: 10.1038/s41467-021-22168-2. Nat Commun. 2021. PMID: 33795677 Free PMC article.
DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.
Roy R, Ramamoorthy S, Shapiro BD, Kaileh M, Hernandez D, Sarantopoulou D, Arepalli S, Boller S, Singh A, Bektas A, Kim J, Moore AZ, Tanaka T, McKelvey J, Zukley L, Nguyen C, Wallace T, Dunn C, Wersto R, Wood W, Piao Y, Becker KG, Coletta C, De S, Sen JM, Battle A, Weng NP, Grosschedl R, Ferrucci L, Sen R. Roy R, et al. Among authors: de s. Immunity. 2021 Nov 9;54(11):2465-2480.e5. doi: 10.1016/j.immuni.2021.10.001. Epub 2021 Oct 26. Immunity. 2021. PMID: 34706222 Free PMC article.
A BDNF-TrkB autocrine loop enhances senescent cell viability.
Anerillas C, Herman AB, Munk R, Garrido A, Lam KG, Payea MJ, Rossi M, Tsitsipatis D, Martindale JL, Piao Y, Mazan-Mamczarz K, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: de cabo r, de s. Nat Commun. 2022 Oct 20;13(1):6228. doi: 10.1038/s41467-022-33709-8. Nat Commun. 2022. PMID: 36266274 Free PMC article.
Author Correction: A BDNF-TrkB autocrine loop enhances senescent cell viability.
Anerillas C, Herman AB, Munk R, Garrido A, Lam KG, Payea MJ, Rossi M, Tsitsipatis D, Martindale JL, Piao Y, Mazan-Mamczarz K, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: de cabo r, de s. Nat Commun. 2022 Dec 7;13(1):7540. doi: 10.1038/s41467-022-35154-z. Nat Commun. 2022. PMID: 36477003 Free PMC article. No abstract available.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: de cabo r, de s. Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116496 Free PMC article.
2,228 results