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Page 1
A targeted delivery strategy for the development of potent trypanocides.
Gordhan HM, Milanes JE, Qiu Y, Golden JE, Christensen KA, Morris JC, Whitehead DC. Gordhan HM, et al. Among authors: milanes je. Chem Commun (Camb). 2017 Aug 11;53(62):8735-8738. doi: 10.1039/c7cc03378h. Epub 2017 Jul 20. Chem Commun (Camb). 2017. PMID: 28726862 Free PMC article.
Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase.
Milanes JE, Suryadi J, Abendroth J, Van Voorhis WC, Barrett KF, Dranow DM, Phan IQ, Patrick SL, Rozema SD, Khalifa MM, Golden JE, Morris JC. Milanes JE, et al. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02410-18. doi: 10.1128/AAC.02410-18. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30783001 Free PMC article.
Characterization of Glucokinases from Pathogenic Free-Living Amoebae.
Milanes JE, Suryadi J, Monaghan NP, Harding EM, Morris CS, Rozema SD, Khalifa MM, Golden JE, Phan IQ, Zigweid R, Abendroth J, Rice CA, McCord HT, Wilson S, Fenwick MK, Morris JC. Milanes JE, et al. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0237321. doi: 10.1128/aac.02373-21. Epub 2022 May 23. Antimicrob Agents Chemother. 2022. PMID: 35604214 Free PMC article.
Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases.
Kassu M, Parvatkar PT, Milanes J, Monaghan NP, Kim C, Dowgiallo M, Zhao Y, Asakawa AH, Huang L, Wagner A, Miller B, Carter K, Barrett KF, Tillery LM, Barrett LK, Phan IQ, Subramanian S, Myler PJ, Van Voorhis WC, Leahy JW, Rice CA, Kyle DE, Morris J, Manetsch R. Kassu M, et al. ACS Infect Dis. 2023 Nov 10;9(11):2190-2201. doi: 10.1021/acsinfecdis.3c00284. Epub 2023 Oct 11. ACS Infect Dis. 2023. PMID: 37820055 Free PMC article.
Enolase Inhibitors as Early Lead Therapeutics against Trypanosoma brucei.
Roster CP, LaVigne D, Milanes JE, Knight E, Anderson HD, Pizarro S, Harding EM, Morris MT, Yan VC, Pham CD, Muller F, Kwain S, Rees KC, Dominy B, Whitehead DC, Uddin MN, Millward SW, Morris JC. Roster CP, et al. Among authors: milanes je. Pathogens. 2023 Oct 28;12(11):1290. doi: 10.3390/pathogens12111290. Pathogens. 2023. PMID: 38003754 Free PMC article.
Enolase inhibitors as therapeutic leads for Naegleria fowleri infection.
Milanes JE, Yan VC, Pham CD, Muller F, Kwain S, Rees KC, Dominy BN, Whitehead DC, Millward SW, Bolejack M, Abendroth J, Phan IQ, Staker B, Moseman EA, Zhang X, Ma X, Jebet A, Yin X, Morris JC. Milanes JE, et al. bioRxiv [Preprint]. 2024 Jan 17:2024.01.16.575558. doi: 10.1101/2024.01.16.575558. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Aug 1;20(8):e1012412. doi: 10.1371/journal.ppat.1012412 PMID: 38293107 Free PMC article. Updated. Preprint.
Enolase inhibitors as therapeutic leads for Naegleria fowleri infection.
Milanes JE, Yan VC, Pham CD, Muller F, Kwain S, Rees KC, Dominy BN, Whitehead DC, Millward SW, Bolejack M, Shek R, Tillery L, Phan IQ, Staker B, Moseman EA, Zhang X, Ma X, Jebet A, Yin X, Morris JC. Milanes JE, et al. PLoS Pathog. 2024 Aug 1;20(8):e1012412. doi: 10.1371/journal.ppat.1012412. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39088549 Free PMC article.
12 results