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Page 1
The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5.
Maven BEJ, Gifford CA, Weilert M, Gonzalez-Teran B, Hüttenhain R, Pelonero A, Ivey KN, Samse-Knapp K, Kwong W, Gordon D, McGregor M, Nishino T, Okorie E, Rossman S, Costa MW, Krogan NJ, Zeitlinger J, Srivastava D. Maven BEJ, et al. Among authors: krogan nj. Stem Cell Reports. 2023 Nov 14;18(11):2138-2153. doi: 10.1016/j.stemcr.2023.09.014. Epub 2023 Oct 19. Stem Cell Reports. 2023. PMID: 37863045 Free PMC article.
A proximity proteomics pipeline with improved reproducibility and throughput.
Zhong X, Li Q, Polacco BJ, Patil T, Marley A, Foussard H, Khare P, Vartak R, Xu J, DiBerto JF, Roth BL, Eckhardt M, Zastrow MV, Krogan NJ, Hüttenhain R. Zhong X, et al. Among authors: krogan nj. bioRxiv [Preprint]. 2024 Apr 27:2023.04.11.536358. doi: 10.1101/2023.04.11.536358. bioRxiv. 2024. Update in: Mol Syst Biol. 2024 Aug;20(8):952-971. doi: 10.1038/s44320-024-00049-2 PMID: 37090610 Free PMC article. Updated. Preprint.
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JNG, Souza CDS, Zhang S, Azzouz M, Gordon D, Krogan N, Ferraiuolo L, Snyder MP, Shaw PJ, Rehwinkel J, Cooper-Knock J. Moll T, et al. bioRxiv [Preprint]. 2022 Mar 7:2022.03.06.483172. doi: 10.1101/2022.03.06.483172. bioRxiv. 2022. Update in: Life Sci Alliance. 2022 Oct 14;6(1):e202201449. doi: 10.26508/lsa.202201449 PMID: 35291294 Free PMC article. Updated. Preprint.
SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, Stevenson E, Rojc A, Ragazzini R, Whelan MVX, Furnon W, De Lorenzo G, Cowton V, Syed AM, Ciling A, Deutsch N, Pirak D, Dowgier G, Mesner D, Turner JL, McGovern BL, Rodriguez ML, Leiva-Rebollo R, Dunham AS, Zhong X, Eckhardt M, Fossati A, Liotta NF, Kehrer T, Cupic A, Rutkowska M, Mena I, Aslam S, Hoffert A, Foussard H, Olwal CO, Huang W, Zwaka T, Pham J, Lyons M, Donohue L, Griffin A, Nugent R, Holden K, Deans R, Aviles P, Lopez-Martin JA, Jimeno JM, Obernier K, Fabius JM, Soucheray M, Hüttenhain R, Jungreis I, Kellis M, Echeverria I, Verba K, Bonfanti P, Beltrao P, Sharan R, Doudna JA, Martinez-Sobrido L, Patel AH, Palmarini M, Miorin L, White K, Swaney DL, Garcia-Sastre A, Jolly C, Zuliani-Alvarez L, Towers GJ, Krogan NJ. Bouhaddou M, et al. Among authors: krogan nj. Cell. 2023 Oct 12;186(21):4597-4614.e26. doi: 10.1016/j.cell.2023.08.026. Epub 2023 Sep 21. Cell. 2023. PMID: 37738970 Free PMC article.
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. Arang N, et al. Among authors: krogan nj. Cell Rep Med. 2023 Nov 21;4(11):101244. doi: 10.1016/j.xcrm.2023.101244. Epub 2023 Oct 18. Cell Rep Med. 2023. PMID: 37858338 Free PMC article.
Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy.
Krause GJ, Kirchner P, Stiller B, Morozova K, Diaz A, Chen KH, Krogan NJ, Agullo-Pascual E, Clement CC, Lindenau K, Swaney DL, Dilipkumar S, Bravo-Cordero JJ, Santambrogio L, Cuervo AM. Krause GJ, et al. Among authors: krogan nj. Cell Rep. 2023 Dec 26;42(12):113529. doi: 10.1016/j.celrep.2023.113529. Epub 2023 Dec 6. Cell Rep. 2023. PMID: 38060380 Free PMC article.
ATG7(2) Interacts With Metabolic Proteins and Regulates Central Energy Metabolism.
Ostacolo K, López García de Lomana A, Larat C, Hjaltalin V, Holm KY, Hlynsdóttir SS, Soucheray M, Sooman L, Rolfsson O, Krogan NJ, Steingrimsson E, Swaney DL, Ogmundsdottir MH. Ostacolo K, et al. Among authors: krogan nj. Traffic. 2024 Apr;25(4):e12933. doi: 10.1111/tra.12933. Traffic. 2024. PMID: 38600522 Free PMC article.
MerlinS13 phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features.
Eaton C, Avalos L, Liu SJ, Casey-Clyde T, Bisignano P, Lucas CH, Stevenson E, Choudhury A, Vasudevan H, Magill S, Krogan N, Villanueva-Meyer J, Swaney D, Raleigh D. Eaton C, et al. Res Sq [Preprint]. 2023 Mar 14:rs.3.rs-2577844. doi: 10.21203/rs.3.rs-2577844/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Sep 9;15(1):7873. doi: 10.1038/s41467-024-52284-8 PMID: 36993679 Free PMC article. Updated. Preprint.
373 results