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A single amino acid residue in bank vole prion protein drives permissiveness to Nor98/atypical scrapie and the emergence of multiple strain variants.
Pirisinu L, Di Bari MA, D'Agostino C, Vanni I, Riccardi G, Marcon S, Vaccari G, Chiappini B, Benestad SL, Agrimi U, Nonno R. Pirisinu L, et al. Among authors: vanni i. PLoS Pathog. 2022 Jun 22;18(6):e1010646. doi: 10.1371/journal.ppat.1010646. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35731839 Free PMC article.
A tetracationic porphyrin with dual anti-prion activity.
Masone A, Zucchelli C, Caruso E, Lavigna G, Eraña H, Giachin G, Tapella L, Comerio L, Restelli E, Raimondi I, Elezgarai SR, De Leo F, Quilici G, Taiarol L, Oldrati M, Lorenzo NL, García-Martínez S, Cagnotto A, Lucchetti J, Gobbi M, Vanni I, Nonno R, Di Bari MA, Tully MD, Cecatiello V, Ciossani G, Pasqualato S, Van Anken E, Salmona M, Castilla J, Requena JR, Banfi S, Musco G, Chiesa R. Masone A, et al. Among authors: vanni i. iScience. 2023 Jul 27;26(9):107480. doi: 10.1016/j.isci.2023.107480. eCollection 2023 Sep 15. iScience. 2023. PMID: 37636075 Free PMC article.
Studies in bank voles reveal strain differences between chronic wasting disease prions from Norway and North America.
Nonno R, Di Bari MA, Pirisinu L, D'Agostino C, Vanni I, Chiappini B, Marcon S, Riccardi G, Tran L, Vikøren T, Våge J, Madslien K, Mitchell G, Telling GC, Benestad SL, Agrimi U. Nonno R, et al. Among authors: vanni i. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31417-31426. doi: 10.1073/pnas.2013237117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229531 Free PMC article.
In vitro replication highlights the mutability of prions.
Vanni I, Di Bari MA, Pirisinu L, D'Agostino C, Agrimi U, Nonno R. Vanni I, et al. Prion. 2014 Jan-Feb;8(1):154-60. doi: 10.4161/pri.28468. Epub 2014 Mar 11. Prion. 2014. PMID: 24618479 Free PMC article.
76 results