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Synthesis of a gemcitabine-modified phospholipid and its subsequent incorporation into a single microbubble formulation loaded with paclitaxel for the treatment of pancreatic cancer using ultrasound-targeted microbubble destruction.
Logan KA, Nesbitt H, Callan B, Gao J, McKaig T, Taylor M, Love M, McHale AP, Callan JF. Logan KA, et al. Among authors: mckaig t. Eur J Pharm Biopharm. 2021 Aug;165:374-382. doi: 10.1016/j.ejpb.2021.05.018. Epub 2021 May 24. Eur J Pharm Biopharm. 2021. PMID: 34038797
A single microbubble formulation carrying 5-fluorouridine, Irinotecan and oxaliplatin to enable FOLFIRINOX treatment of pancreatic and colon cancer using ultrasound targeted microbubble destruction.
Gao J, Logan KA, Nesbitt H, Callan B, McKaig T, Taylor M, Love M, McHale AP, Griffith DM, Callan JF. Gao J, et al. Among authors: mckaig t. J Control Release. 2021 Oct 10;338:358-366. doi: 10.1016/j.jconrel.2021.08.050. Epub 2021 Sep 1. J Control Release. 2021. PMID: 34481018