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Editorial overview: Recent advances in metabolomics.
McCullagh JSO, Keun HC. McCullagh JSO, et al. Among authors: keun hc. Curr Opin Chem Biol. 2024 Aug;81:102498. doi: 10.1016/j.cbpa.2024.102498. Epub 2024 Jul 8. Curr Opin Chem Biol. 2024. PMID: 38981158 No abstract available.
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts.
Rothwell JA, Bešević J, Dimou N, Breeur M, Murphy N, Jenab M, Wedekind R, Viallon V, Ferrari P, Achaintre D, Gicquiau A, Rinaldi S, Scalbert A, Huybrechts I, Prehn C, Adamski J, Cross AJ, Keun H, Chadeau-Hyam M, Boutron-Ruault MC, Overvad K, Dahm CC, Nøst TH, Sandanger TM, Skeie G, Zamora-Ros R, Tsilidis KK, Eichelmann F, Schulze MB, van Guelpen B, Vidman L, Sánchez MJ, Amiano P, Ardanaz E, Smith-Byrne K, Travis R, Katzke V, Kaaks R, Derksen JWG, Colorado-Yohar S, Tumino R, Bueno-de-Mesquita B, Vineis P, Palli D, Pasanisi F, Eriksen AK, Tjønneland A, Severi G, Gunter MJ. Rothwell JA, et al. BMC Med. 2023 Feb 28;21(1):80. doi: 10.1186/s12916-023-02739-4. BMC Med. 2023. PMID: 36855092 Free PMC article.
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Fogal V, Michopoulos F, Jarnuczak AF, Hamza GM, Harlfinger S, Davey P, Hulme H, Atkinson SJ, Gabrowski P, Cheung T, Grondine M, Hoover C, Rose J, Bray C, Foster AJ, Askin S, Majumder MM, Fitzpatrick P, Miele E, Macdonald R, Keun HC, Coen M. Fogal V, et al. Among authors: keun hc. Arch Toxicol. 2024 Aug;98(8):2589-2603. doi: 10.1007/s00204-024-03771-w. Epub 2024 May 17. Arch Toxicol. 2024. PMID: 38755480 Free PMC article.
Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants.
Stratakis N, Anguita-Ruiz A, Fabbri L, Maitre L, González JR, Andrusaityte S, Basagaña X, Borràs E, Keun HC, Chatzi L, Conti DV, Goodrich J, Grazuleviciene R, Haug LS, Heude B, Yuan WL, McEachan R, Nieuwenhuijsen M, Sabidó E, Slama R, Thomsen C, Urquiza J, Roumeliotaki T, Vafeiadi M, Wright J, Bustamante M, Vrijheid M. Stratakis N, et al. Among authors: keun hc. Nat Commun. 2025 Jan 14;16(1):654. doi: 10.1038/s41467-025-56013-7. Nat Commun. 2025. PMID: 39809770 Free PMC article.
PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma.
Spear S, Le Saux O, Mirza HB, Iyer N, Tyson K, Grundland Freile F, Walton JB, Woodman C, Jarvis S, Ennis DP, Aguirre Hernandez C, Xu Y, Spiliopoulou P, Brenton JD, Costa-Pereira AP, Cook DP, Vanderhyden BC, Keun HC, Triantafyllou E, Arnold JN, McNeish IA. Spear S, et al. Among authors: keun hc. Cancer Res. 2024 Nov 15;84(22):3772-3787. doi: 10.1158/0008-5472.CAN-23-3890. Cancer Res. 2024. PMID: 39186679 Free PMC article.
151 results