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Page 1
Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation.
Riwes MM, Golob JL, Magenau J, Shan M, Dick G, Braun T, Schmidt TM, Pawarode A, Anand S, Ghosh M, Maciejewski J, King D, Choi S, Yanik G, Geer M, Hillman E, Lyssiotis CA, Tewari M, Reddy P. Riwes MM, et al. Among authors: lyssiotis ca. Nat Med. 2023 Nov;29(11):2805-2813. doi: 10.1038/s41591-023-02587-y. Epub 2023 Oct 19. Nat Med. 2023. PMID: 37857710 Free PMC article. Clinical Trial.
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Bian Y, Li W, Kremer DM, Sajjakulnukit P, Li S, Crespo J, Nwosu ZC, Zhang L, Czerwonka A, Pawłowska A, Xia H, Li J, Liao P, Yu J, Vatan L, Szeliga W, Wei S, Grove S, Liu JR, McLean K, Cieslik M, Chinnaiyan AM, Zgodziński W, Wallner G, Wertel I, Okła K, Kryczek I, Lyssiotis CA, Zou W. Bian Y, et al. Among authors: lyssiotis ca. Nature. 2020 Sep;585(7824):277-282. doi: 10.1038/s41586-020-2682-1. Epub 2020 Sep 2. Nature. 2020. PMID: 32879489 Free PMC article.
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
Devenport SN, Singhal R, Radyk MD, Taranto JG, Kerk SA, Chen B, Goyert JW, Jain C, Das NK, Oravecz-Wilson K, Zhang L, Greenson JK, Chen YE, Soleimanpour SA, Reddy P, Lyssiotis CA, Shah YM. Devenport SN, et al. Among authors: lyssiotis ca. JCI Insight. 2021 Jun 17;6(14):e138835. doi: 10.1172/jci.insight.138835. JCI Insight. 2021. PMID: 34138755 Free PMC article.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: lyssiotis ca. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee HJ, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P. Fujiwara H, et al. Among authors: lyssiotis ca. Nat Immunol. 2021 Nov;22(11):1440-1451. doi: 10.1038/s41590-021-01048-3. Epub 2021 Oct 22. Nat Immunol. 2021. PMID: 34686860 Free PMC article.
Unravelling specific diet and gut microbial contributions to inflammatory bowel disease.
Pereira GV, Boudaud M, Wolter M, Alexander C, De Sciscio A, Grant ET, Trindade BC, Pudlo NA, Singh S, Campbell A, Shan M, Zhang L, Willieme S, Kim K, Denike-Duval T, Bleich A, Schmidt TM, Kennedy L, Lyssiotis CA, Chen GY, Eaton KA, Desai MS, Martens EC. Pereira GV, et al. Among authors: lyssiotis ca. Res Sq [Preprint]. 2023 Mar 13:rs.3.rs-2518251. doi: 10.21203/rs.3.rs-2518251/v1. Res Sq. 2023. PMID: 36993463 Free PMC article. Preprint.
Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions.
Alektiar JM, Shan M, Radyk MD, Zhang L, Halbrook CJ, Lin L, Espinoza C, Mier IF, Lavoie BL, Salvatore L, Pasca di Magliano M, Cantley LC, Mueller JL, Lyssiotis CA. Alektiar JM, et al. Among authors: lyssiotis ca. PLoS One. 2024 Jun 6;19(6):e0303577. doi: 10.1371/journal.pone.0303577. eCollection 2024. PLoS One. 2024. PMID: 38843233 Free PMC article.
Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma.
Mbah NE, Myers AL, Sajjakulnukit P, Chung C, Thompson JK, Hong HS, Giza H, Dang D, Nwosu ZC, Shan M, Sweha SR, Maydan DD, Chen B, Zhang L, Magnuson B, Zhu Z, Radyk M, Lavoie B, Yadav VN, Koo I, Patterson AD, Wahl DR, Franchi L, Agnihotri S, Koschmann CJ, Venneti S, Lyssiotis CA. Mbah NE, et al. Among authors: lyssiotis ca. Nat Commun. 2024 Oct 17;15(1):8983. doi: 10.1038/s41467-024-52973-4. Nat Commun. 2024. PMID: 39419964 Free PMC article.
208 results